Influenza Vaccine Uptake Among Healthcare Workers

NCT05521763 | Unknown DMC

• 1 other identifier: PR-21150
• Study Type: interventional
• Target: 3,000
• Locations: 1 country
• Sites: 1

Brief Summary

Background:

1. 1.Burden: Health-care workers (HCWs), such as doctors, nurses, and support staff involved in direct or indirect patient care, are at increased risk of influenza virus infections. HCWs may also transmit and spread influenza among hospitalized patients and other caregivers. HCWs often (40-83%) work while experiencing influenza-like illness (ILI), increasing the likelihood of influenza transmission to colleagues and patients.
2. 2.Knowledge gap: Despite the World Health Organization recommendation for seasonal influenza vaccination among priority target groups such as health care workers, the low-income country such as Bangladesh lacks a seasonal influenza vaccination policy among this high-risk group, and vaccine uptake remains low.
3. 3.Relevance: This study aims to generate preliminary data on HCWs willingness to get seasonal influenza vaccines following vaccine availability and factors associated with vaccine uptakes. The data from the study will support policymakers to increase awareness and develop influenza vaccination policy among top priority groups such as health care workers.
4. 4.To assess influenza vaccine uptake among healthcare workers (HCWs) following awareness and availability of influenza vaccine supply in study hospitals
5. 5.To explore HCWs barriers and Motivators for influenza vaccine uptake
6. 6.To understand policy makers' perspectives on the feasibility of influenza vaccination among HCWs and to share with the National Immunization Technical Advisory Group (NITAG) for a policy decision regarding influenza vaccination
7. 7.The proportion of influenza vaccine uptake among health care workers before and after intervention and between different study arms
8. 8.Different motivators and barriers to influenza vaccine uptake

Conditions

Influenza Vaccines

Keywords

Vaccination Awareness; Healthcare Workers

Outcome Measures

Primary Outcomes (1)

• Influenza vaccine uptake among HCWs

  The proportion of influenza vaccine uptake among health care workers before and after intervention and between different study arms

  up to 4 months

Secondary Outcomes (1)

• Motivators and barriers of influenza vaccine uptake

  up to 4 months

Study Arms (4)

Intervention package with the availability of vaccine supply only

EXPERIMENTAL

1. The investigators will work with the supplier to make that vaccine available at the hospital premises. Then a vaccination booth will be set up at the hospital premises and will administer the vaccine at the MRP. 2. All HCWs will be notified about only vaccine availability information by the hospital director and respective heads. 3. A list of all staff working in the study hospitals will be prepared, and they will be provided with an influenza vaccination record card with a unique identification number. The study staff will ensure receipt of vaccination cards for all participants. 4. A short message (SMS) will be delivered over the mobile phone number to all participants, e.g. vaccination program duration, venue, time, vaccine price, to cascade vaccination information to participants. 5. Posters with only vaccine delivery information (i.e. vaccination duration, vaccination venue, vaccine price) will be displayed at key hospital locations.

Behavioral: ensuring the availability of influenza vaccine supply & developing influenza vaccine awareness

Intervention package with vaccinationation awareness only

EXPERIMENTAL

1. The hospital director and respective heads will notify all HCWs about participating in the vaccination awareness program facilitated by the study team. 2. The investigators will arrange separate seminars for each group of HCWs in the hospital to sensitize participants about the significance of receiving the influenza vaccine and the risk and benefits of influenza vaccination. 3. Posters containing messages on the importance of influenza vaccination will be displayed at key hospital locations, e.g., the main entrance of the hospital, nursing station, vaccine delivery point/place, doctors' room, nurses' room, intern doctors' room, common room canteen etc.

Behavioral: ensuring the availability of influenza vaccine supply & developing influenza vaccine awareness

Intervention package with a combination of vaccine availability and awareness

EXPERIMENTAL

1. The investigators will work with the study hospital authority, Influenza vaccine manufacturer, and supplier company to set up a vaccination booth at the hospital premises to administer the vaccine at the market-rated price (MRP) by hospital nurses. 2. The hospital director and respective department heads will notify all HCWs to receive the offered influenza vaccine. 3. A list of all staff working in the study hospitals will be prepared, and they will be provided with an influenza vaccination record card with a unique identification number. 4. The investigators will arrange separate seminars for each group of HCWs in the hospital to sensitize participants about the significance of receiving the influenza vaccine and the risk and benefits of influenza vaccination. 5. A short message (SMS) will be delivered over the mobile phone number to all participants. 6. Posters with key messages will be displayed at key hospital locations,

Behavioral: ensuring the availability of influenza vaccine supply & developing influenza vaccine awareness

No intervention

NO INTERVENTION

In the control facility, we will not intervene in the existing knowledge and practice about influenza vaccination of the HCWs.

Interventions

ensuring the availability of influenza vaccine supply & developing influenza vaccine awareness BEHAVIORAL

The four interventions will be: i) ensuring the availability of influenza vaccine supply; ii) developing influenza vaccine awareness; iii) both ensuring influenza vaccine supply and developing influenza vaccine awareness and iv) control arm with no intervention.

Intervention package with a combination of vaccine availability and awareness; Intervention package with the availability of vaccine supply only; Intervention package with vaccinationation awareness only

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• All HCWs who will be working at the study hospitals during the intervention period as well as consented to participate in the study will be included as participants

You may not qualify if:

• HCWs not directly or indirectly involved in patient care, such as basic medical science faculties (e.g. anatomy, physiology, biochemistry, forensic medicine, pathology, and microbiology), will not be included as participants

Sponsors & Collaborators

• International Centre for Diarrhoeal Disease Research, Bangladesh: lead
• Institute of Epidemiology, Disease Control and Research: collaborator
• Sylhet M.A.G.Osmani Medical College: collaborator
• Mymensingh Medical College Hospital: collaborator
• Rajshahi Medical College: collaborator
• Khulna Medical College Hospital: collaborator
• Centers for Disease Control and Prevention: collaborator

Study Sites (1)

Sylhet MAG Osmani Medical College Hospital

Sylhet, Bangladesh

RECRUITING

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Related Links

• WHO seasonal influenza vaccination recommendations during the COVID-19 pandemic - Recommandations du SAGE de l'OMS pour la vaccination contre la grippe saisonnière pendant la pandémie de COVID-19
• Seasonal influenza vaccine use in low and middle income countries in the tropics and subtropics: a systematic review
• Health conditions for travellers to Saudi Arabia Pilgrimage to Mecca (Hajj) = Dispositions sanitaires pour les voyageurs se rendant en Arabie saoudite Pèlerinage à La Mecque (Hadj)
• Global Influenza Strategy 2019-2030

MeSH Terms

Conditions

Influenza, Human

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Orthomyxoviridae Infections; RNA Virus Infections; Virus Diseases; Respiratory Tract Diseases

Central Study Contacts

Dr Md Zakiul Hassan, MSc

CONTACT

+8802222277001-10; zhassan@icddrb.org

Dr Fahmida Chowdhury, MPH

CONTACT

+8802222277001-10; fahmida_chow@icddrb.org

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 17, 2022
• First Posted: August 30, 2022
• Study Start: March 12, 2022
• Primary Completion: December 29, 2022
• Study Completion: February 12, 2023
• Last Updated: September 15, 2022

Record last verified: 2022-08

Data Sharing

• IPD Sharing: Will not share

Locations

BA (1)