Laparoscopic Pancreatoduodenectomy Versus Open Pancreatoduodenectomy
Minimally Invasive Versus Open for Pancreatoduodenectomy：an Retrospective, Observational, Multicenter Real-world Study
1 other identifier
observational
800
0 countries
N/A
Brief Summary
This is a single, retrospective, real-world study to investigate the surgical outcomes of minimally invasive pancreatoduodenectomy and open pancreatoduodenectomy, with the perioperative characteristics and long-term overall survival being compared. The investigators aimed to find out whether the minimally invasive surgery is safe and feasible for resectable lesions located in the pancreatic head and periampullary region. And the investigators also want to find out patients with what kind of characteristic can be benefit from the minimally invasive surgery compared with the open approach.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2014
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 30, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2021
CompletedFirst Submitted
Initial submission to the registry
August 19, 2022
CompletedFirst Posted
Study publicly available on registry
August 30, 2022
CompletedAugust 30, 2022
August 1, 2022
6 years
August 19, 2022
August 29, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Postoperative length of stay
defined as the time from being admitted to hospital to discharge
up to 90 days
Secondary Outcomes (8)
Overall survival
through study completion, an average of 5 year
Operation time
intraoperative
postoperative complications
up to 90 days
Reoperation within 90 days
up to 90 days
Mortality
up to 90 days
- +3 more secondary outcomes
Study Arms (2)
minimally invasive surgery
laparoscopic pancreatoduodenectomy.
open surgery
open pancreatoduodenectomy
Interventions
Pancreatoduodenectomy (Whipple surgery) is a complex surgical procedure and has been accepted as the gold standard treatment for resectable lesions of the pancreatic head and periampullary region
Eligibility Criteria
Patients who underwent PD surgeries in Tongji Hospital since January 2014 .
You may qualify if:
- Aged 18 to 80 years.
- Patients underwent PD surgeries.
You may not qualify if:
- Peritoneal seeding or metastasis to distant sites;
- Incomplete clinical data.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Tongji Hospitallead
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor in Surgery, Chief Physician, Director of Surgical Supervision Department, Deputy Director of Institute of Hepatobiliary&Pancreatic, Director of Department of Biliary-Pancreatic Surgery
Study Record Dates
First Submitted
August 19, 2022
First Posted
August 30, 2022
Study Start
January 1, 2014
Primary Completion
December 30, 2019
Study Completion
December 30, 2021
Last Updated
August 30, 2022
Record last verified: 2022-08