Radiologic Score and Failure of Conservative Management of Adhesive Small Bowel Obstruction

NCT05517057 | Completed

• 1 other identifier: 2021-099
• Study Type: observational
• Target: 279
• Locations: 1 country
• Sites: 1

Brief Summary

The management of acute adhesive small bowel obstruction remains challenging for the digestive surgeon. The Bologna guidelines recommend that conservative management of aSBO. The literature reports that this form of management has a failure rate between 10 and 40%. A radiological score has been proposed and was associated with an increased risk of failure of conservative management. This tool is promising to select patients further requiring surgery but it has to be assessed in a multi centric prospective cohort.

Conditions

Small Bowel Obstruction; Conservative Management; Imaging

Outcome Measures

Primary Outcomes (1)

• Angers CT score

  The Angers CT score ≥5 was considered to be risk factor for failure of the medical management. Angers CT score was calculated by reading the CT scan as follow: * beak sign (+2), if not (0) * closed loop (+4), if not (0) * focal (+4) or diffuse (+4) intraperitoneal liquid, if not (0) * focal (+2) or diffuse (0) mesenteric haziness, if not (0) * focal (-3) or diffuse (-3) mesenteric liquid, if not (0) * diameter of the most dilated small bowel loop \> 40 mm (-2) (if not (0).

  immediately after the completion of the CT-scan

Study Arms (2)

success of the medical management

Patients that recovered flatus and stools, and that tolerated solid food within the 3 days after the admission

failure of the medical management

Patients that did not recover flatus and stools, and that did not tolerate solid food within the 3 days after the admission. These patients had an indication for surgery.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This was an observational multicentric cohort study including all the consecutive patients admitted for initial non-surgical management for aSBO. The study took place over a period of 3 months (September 15 - December 15, 2021) in 15 French centers.

You may qualify if:

• all the consecutive patients admitted for initial non-surgical management for aSBO

You may not qualify if:

• the cause of SBO was functional or other than adhesive
• patients requiring initial surgical management.
• absence of computed tomography performed at admission

Sponsors & Collaborators

• University Hospital, Angers: lead

Study Sites (1)

university hospital of Angers

Angers, France

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 20, 2022
• First Posted: August 26, 2022
• Study Start: September 15, 2021
• Primary Completion: December 15, 2021
• Study Completion: January 15, 2022
• Last Updated: August 26, 2022

Record last verified: 2022-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)