PRETERM DELİVERY and MYOCINE BINDING PROTEIN C LEVELs

NCT05513768 | Completed

• 1 other identifier: GaziosmanpasaTREHKHD
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

IT WAS AIMED TO EVALUATE IF MBPC CAN BE USED IN PREDICTION OF EARLY BIRTH. TAKING THE FIRST TRIMESTER FROM PREGNANCY WAS STORED UNTIL THE TIMING OF DELIVERY.THE PARTICIPANTS WERE SEPARATED INTO TWO GROUPS ACCORDING TO THE TIME OF BIRTH, EARLY AND TIMELY. SERUM MBPC LEVELS BETWEEN TWO GROUPS EVALUATED.

Conditions

Preterm

Keywords

PRETERM DELİVERY, MBPC,

Outcome Measures

Primary Outcomes (1)

• detection of prediction value of serum mbpc levels in preterm delivery

  identifying prediction value of first trmester serum mbpc levels by comparing by serum levels of mbpc in groups

  10 mounths

Study Arms (2)

women who gave birth prematurely

women who had serum taken in the first trimester and gave birth earlier than 37 weeks according to the time of delivery

Diagnostic Test: level of myosin binding protein c in serum

those who gave birth on time

women who have had serum taken in the first trimester, stored and delivered on time

Diagnostic Test: level of myosin binding protein c in serum

Interventions

level of myosin binding protein c in serum DIAGNOSTIC_TEST

Serum samples will be taken from the participants in the first trimester, transferred to eppendorf tubes after appropriate procedures, and stored at -80 degrees until the time of deliveryParticipants will be divided into two groups according to the timing of birthThe first group is those who gave birth earlier than 37 weeks those who gave birth on time in the other group The mbpc levels will be looked at and compared.

those who gave birth on time; women who gave birth prematurely

Eligibility Criteria

• Age: 18 Years - 40 Years
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Includes participants whose serum samples were collected in the first trimester, stored, and then divided into two according to timing of delivery fırst grup ıs preterm group, and second one ıs those who gave birth on time

You may qualify if:

• being pregnant in the first trimester
• be between 18-40 years old

You may not qualify if:

• no history of preterm birth
• being pregnant with assisted reproductive techniques
• having a multiple pregnancy
• have cervical insufficiency

Sponsors & Collaborators

• Gaziosmanpasa Research and Education Hospital: lead

Study Sites (1)

Gaziosmanpasa Training and Research Hospital

Istanbul, Gaziosmanpaşa, 32225, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Premature Birth

Condition Hierarchy (Ancestors)

Obstetric Labor, Premature; Obstetric Labor Complications; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases

Study Officials

• elif yıldız

  Gaziosmanpasa Research and Education Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: OTHER
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MEDİCAL DOCTOR

Study Record Dates

• First Submitted: August 22, 2022
• First Posted: August 24, 2022
• Study Start: January 1, 2022
• Primary Completion: October 30, 2022
• Study Completion: October 30, 2022
• Last Updated: November 23, 2022

Record last verified: 2022-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)