NCT05512507

Brief Summary

Rehabilitative Sanomechanics Method (RSM) of exercise designed to restore normal subperiosteal transmission of in-joint pressures and normalizing contact pressures on cartilages, will reduce pain in the affected joints and improve locomotor function.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
15

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2023

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 21, 2022

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 23, 2022

Completed
5 months until next milestone

Study Start

First participant enrolled

January 30, 2023

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2024

Completed
Last Updated

September 9, 2022

Status Verified

August 1, 2022

Enrollment Period

1.9 years

First QC Date

August 21, 2022

Last Update Submit

September 8, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • The WOMAC self-reported pain score .

    80% of patients will report a reduction in pain at the end of the 3-month study based on the 5-point categorical WOMAC pain scale.

    90 days

  • The WOMAC self-reported function score

    80% of patients will report a lowered WOMAC function score based on 5-point categorical WOMAC scale (lower score corresponds to better self-reported function) after the three-month study.

    90 days

Interventions

Physical Therapy Program

Eligibility Criteria

Age40 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Study intends to enroll diversified patient population diagnosed with unilateral osteoarthritis of the knee

You may qualify if:

  • Unilateral knee pain with WOMAC score 6-9.
  • Knee pain, aching or stiffness on most days in the past month and definite radiographic osteoarthritis in the index knee.
  • Morning stiffness \>30 min.
  • Age: 40-75 years of age.
  • More pain in the morning compared to evening.
  • English speakers.
  • Have daily access to an email address and a computer with Internet
  • Allowed to be on prescription or non-prescription medicine for pain during the course of the study.

You may not qualify if:

  • Inability to communicate in English
  • Lower limb injury, surgery, or intra-articular injection in the past 6-months
  • Current pregnancy
  • Have a pacemaker or other internal medical device
  • Cancer not in remission
  • Gout
  • History of stroke affecting lower limb
  • Major trauma
  • Gross knee instability on exam
  • Lumbar radiculopathy affecting symptomatic limb
  • KL radiographic score 4
  • Morphological indications (bone-on-bone contact) for joint replacement

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 21, 2022

First Posted

August 23, 2022

Study Start

January 30, 2023

Primary Completion

December 30, 2024

Study Completion

December 30, 2024

Last Updated

September 9, 2022

Record last verified: 2022-08

Data Sharing

IPD Sharing
Will not share