Aquatic Exercise for Cognition and Mobility in Older Adults

NCT05501249 | Completed

• 1 other identifier: STUDY00001403
• Study Type: interventional
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to assess the effects of an aquatic exercise program on cognition and physical function of older adults.

Conditions

Aging Well; Aging Problems; Cognitive Change; Gait, Unsteady; Mobility Limitation

Keywords

Aquatic exercise; Fall prevention; Functional mobility

Outcome Measures

Primary Outcomes (5)

• Stroop Effect Test: Change from baseline to the end of intervention/control period

  Measure of working memory and attention

  Measures taken at baseline and again at approximately 9-10 weeks

• Trail Making Test A and B: Change from baseline to the end of intervention/control period

  Measure of visual scanning and working memory

  Measures taken at baseline and again at approximately 9-10 weeks

• Digit Backwards Test : Change from baseline to the end of intervention/control period

  Measure of working memory capacity

  Measures taken at baseline and again at approximately 9-10 weeks

• Gait Measurements: Change from baseline to the end of intervention/control period

  4 gait conditions (single task gait, dual task gait with head turns, dual task gait with head nods, and dual task gait count backwards by serial 7s). Gait measures collected with Strideway Gait Analysis System.

  Measures taken at baseline and again at approximately 9-10 weeks

• Functional Outcome Measures: Change from baseline to the end of intervention/control period

  Timed Up and Go Test, Cognitive Timed Up and Go Test, Single Leg Balance Test, and Four Square Step Test.

  Measures taken at baseline and again at approximately 9-10 weeks

Secondary Outcomes (6)

• Vital Sign measurements: Change from baseline to the end of intervention/control period

  Measures taken at baseline and again at approximately 9-10 weeks

• Anthropometric measurements: Change from baseline to the end of intervention/control period

  Measures taken at baseline and again at approximately 9-10 weeks

• Neurotrophic Growth Factors: Change from baseline to the end of intervention/control period

  Measures taken at baseline and again at approximately 9-10 weeks

• Numeric Pain Rating Scale: Change from baseline to the end of intervention/control period

  Measures taken at baseline and again at approximately 9-10 weeks

• Global Rating of Change Questionnaire: Change from baseline to the end of intervention/control period

  Measures taken at baseline and again at approximately 9-10 weeks

Study Arms (2)

Aquatic Exercise Group

EXPERIMENTAL

Aquatic class 45 minutes, 3 times a week, for 8 weeks

Behavioral: Aquatic Integrated Cognitive Motor Training

Control Group

NO INTERVENTION

Usual care for 8 weeks and one hour education session on fall prevention.

Interventions

Aquatic Integrated Cognitive Motor Training BEHAVIORAL

Aquatic exercise class with focus on cognitive and physical exercise

Aquatic Exercise Group

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Able to ambulate 100 ft independently with or without assistive device
• Score greater than or equal to 3 on the Mini-Cog Test
• Stable medical condition within one month prior to the study
• Stable exercise program within one month prior to the study
• Available during study testing and group class times
• COVID-19 vaccination
• Permission from medical provider to participate in the study

You may not qualify if:

• History of dementia or Alzheimer's
• Contraindication to exercise or pool immersion (e.g., unstable cardiovascular conditions, fever, diarrhea, aqua-phobia)

Sponsors & Collaborators

• Emily Dunlap: lead

Study Sites (1)

The University of Texas at Austin

Austin, Texas, 78712, United States

Location

Related Publications (10)

• Carter HH, Spence AL, Pugh CJ, Ainslie P, Naylor LH, Green DJ. Cardiovascular responses to water immersion in humans: impact on cerebral perfusion. Am J Physiol Regul Integr Comp Physiol. 2014 May;306(9):R636-40. doi: 10.1152/ajpregu.00516.2013. Epub 2014 Feb 19.

  PMID: 24553298 BACKGROUND

• Bressel E, Louder TJ, Raikes AC, Alphonsa S, Kyvelidou A. Water Immersion Affects Episodic Memory and Postural Control in Healthy Older Adults. J Geriatr Phys Ther. 2019 Oct/Dec;42(4):E1-E6. doi: 10.1519/JPT.0000000000000192.

  PMID: 29738406 BACKGROUND

• Parfitt R, Hensman MY, Lucas SJE. Cerebral Blood Flow Responses to Aquatic Treadmill Exercise. Med Sci Sports Exerc. 2017 Jul;49(7):1305-1312. doi: 10.1249/MSS.0000000000001230.

  PMID: 28166116 BACKGROUND

• Pugh CJ, Sprung VS, Ono K, Spence AL, Thijssen DH, Carter HH, Green DJ. The effect of water immersion during exercise on cerebral blood flow. Med Sci Sports Exerc. 2015 Feb;47(2):299-306. doi: 10.1249/MSS.0000000000000422.

  PMID: 24977699 BACKGROUND

• Kang DW, Bressel E, Kim DY. Effects of aquatic exercise on insulin-like growth factor-1, brain-derived neurotrophic factor, vascular endothelial growth factor, and cognitive function in elderly women. Exp Gerontol. 2020 Apr;132:110842. doi: 10.1016/j.exger.2020.110842. Epub 2020 Jan 15.

  PMID: 31954186 BACKGROUND

• Commandeur D, Klimstra MD, MacDonald S, Inouye K, Cox M, Chan D, Hundza SR. Difference scores between single-task and dual-task gait measures are better than clinical measures for detection of fall-risk in community-dwelling older adults. Gait Posture. 2018 Oct;66:155-159. doi: 10.1016/j.gaitpost.2018.08.020. Epub 2018 Aug 23.

  PMID: 30195218 BACKGROUND

• de Assis GG, de Almondes KM. Exercise-dependent BDNF as a Modulatory Factor for the Executive Processing of Individuals in Course of Cognitive Decline. A Systematic Review. Front Psychol. 2017 Apr 19;8:584. doi: 10.3389/fpsyg.2017.00584. eCollection 2017.

  PMID: 28469588 BACKGROUND

• Doi T, Shimada H, Makizako H, Tsutsumimoto K, Hotta R, Nakakubo S, Suzuki T. Association of insulin-like growth factor-1 with mild cognitive impairment and slow gait speed. Neurobiol Aging. 2015 Feb;36(2):942-7. doi: 10.1016/j.neurobiolaging.2014.10.035. Epub 2014 Nov 1.

  PMID: 25467636 BACKGROUND

• Nissim M, Hutzler Y, Goldstein A. A walk on water: comparing the influence of Ai Chi and Tai Chi on fall risk and verbal working memory in ageing people with intellectual disabilities - a randomised controlled trial. J Intellect Disabil Res. 2019 Jun;63(6):603-613. doi: 10.1111/jir.12602. Epub 2019 Feb 18.

  PMID: 30775818 BACKGROUND

• Sato D, Seko C, Hashitomi T, Sengoku Y, Nomura T. Differential effects of water-based exercise on the cognitive function in independent elderly adults. Aging Clin Exp Res. 2015 Apr;27(2):149-59. doi: 10.1007/s40520-014-0252-9. Epub 2014 Jun 26.

  PMID: 24965855 BACKGROUND

MeSH Terms

Conditions

Gait Disorders, Neurologic; Mobility Limitation

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Emily Dunlap, BS

  The University of Texas at Austin

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 10, 2022
• First Posted: August 15, 2022
• Study Start: February 1, 2022
• Primary Completion: December 12, 2022
• Study Completion: December 12, 2022
• Last Updated: March 1, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, CSR, ANALYTIC CODE
• Time Frame: The data will become available after publication
• Access Criteria: Data will be available to researcher for meta-analysis purpose upon reasonable request.

Locations

US (1)