NCT05499494

Brief Summary

The aim of the study is to evaluate the clinical performance of new bioactive injectable composite compared to nanohybrid composite during the restoration of posterior cavities

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
26

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2022

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

August 11, 2022

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 12, 2022

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2024

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2024

Completed
Last Updated

August 15, 2022

Status Verified

August 1, 2022

Enrollment Period

1.5 years

First QC Date

August 11, 2022

Last Update Submit

August 11, 2022

Conditions

Keywords

Injectable compositeNano hybrid composite

Outcome Measures

Primary Outcomes (1)

  • Change in the clinical performance

    Measured using modified USPHS criteria

    From baseline to 18 months

Study Arms (2)

injectable composite

EXPERIMENTAL

The material will be applied according to manufacturer instructions. BEAUTIFIL Flow Plus X will be applied directly into the cavity and create the shape desired in layers not exceeding 2 mm, and light cured for 20 seconds.

Other: Beautifil Flow Plus X F00 injectable composite

Nanohybrid resin composite

ACTIVE COMPARATOR

The nanohybrid resin composite will be applied to the the cavity using the conventional incremental technique according to manufacturer instructions.

Other: Tetric N ceram resin composite

Interventions

bioactive injectable composite

injectable composite

Nano hybrid resin composite

Nanohybrid resin composite

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Participants:
  • Age range 20-50 years.
  • Males Or females .
  • Co-operative patients approving to participate in the trial.
  • Teeth:
  • class I or II carious lesions premolars and molars.
  • Vital upper or lower teeth with no signs of irreversible pulpitis and pulpal necrosis.
  • Presence of favorable occlusion and teeth are in normal contact with the adjacent teeth.

You may not qualify if:

  • Participants:
  • Patients with general systemic illness.
  • Allergic history against any component of used material.
  • Disabilities.
  • Pregnancy
  • Xerostomia.
  • Lack of compliance.
  • Evidence of parafunctional habits.
  • Temporomandibular joint disorders.
  • Teeth:
  • Periapical pathology or signs of pulpal pathology.
  • Endodontically treated teeth.
  • Tooth hypersensitivity.
  • Possible prosthodontic restoration of teeth.
  • Heavy occlusion and occlusal contacts or history of bruxism.
  • +1 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of dentistry, Cairo University

Cairo, Egypt

Location

Study Officials

  • Mai Mamdouh, PhD

    Cairo University

    STUDY DIRECTOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant lecturer at operative dentistry

Study Record Dates

First Submitted

August 11, 2022

First Posted

August 12, 2022

Study Start

August 1, 2022

Primary Completion

February 1, 2024

Study Completion

March 1, 2024

Last Updated

August 15, 2022

Record last verified: 2022-08

Locations