NCT05499078

Brief Summary

As the medical device is CE marked, the objective of this study is to provide performance and safety data on SULFEX 13081.22 nasal spray as close as possible to the routine care.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2022

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 6, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

August 12, 2022

Completed
21 days until next milestone

Study Start

First participant enrolled

September 2, 2022

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2023

Completed
Last Updated

March 3, 2023

Status Verified

July 1, 2022

Enrollment Period

1.1 years

First QC Date

July 6, 2022

Last Update Submit

March 2, 2023

Conditions

Keywords

Nasal ObstructionNasal Obstruction, BilateralNasal BleedingNasal Passage IrritationNasal PainNasal CrustingNasal ItchingNasal BurningNasal DiscomfortSneezingAirborne particlesMucous Membrane

Outcome Measures

Primary Outcomes (1)

  • Nasal symptoms severity

    Severity of the following nasal symptoms will be compared before and 6 days after spray use on a 7-point scale basis. * Nasal irritation * Nasal dryness Performance on Irritation and Dryness will be verified if there is a decrease of at least 0.5 point on at least one of the two symptom scores between Day 0 and Day 6. This item is scaled from 0 to 3, with 0.5 increments and 3 being the worst value.

    6 days

Secondary Outcomes (9)

  • Safety data on SULFEX 13081.22 nasal spray

    6 days

  • Performance of SULFEX 13081.22 nasal spray

    6 days

  • Nasal symptoms relief/change

    6 days

  • Onset of relief

    immediate or semi-immediate

  • Duration of relief (long lasting).

    6 days

  • +4 more secondary outcomes

Study Arms (1)

SULFEX 13081.22

EXPERIMENTAL

Patients with dry or irritated nose treated with SULFEX 13081.22 nasal spray for 6 days (with at least 1 spray use a day).

Device: SULFEX 13081.22

Interventions

Patients with dry or irritated nose treated with SULFEX 13081.22 nasal spray for 6 days (with at least 1 spray use a day). Severity of the nasal symptoms will be compared before and 6 days after spray use on a 7-point nasal symptoms scale basis.

SULFEX 13081.22

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient \> 18 years of age.
  • Patient voluntarily buying the spray and using it for him/herself.
  • Patient with nasal dryness and/or nasal irritation.
  • Patient informed of the study, who gave its express consent (free, informed, written) before any specific procedure to the study.
  • Patient meeting study's requirements regarding follow-up schedule and questionnaires filling.
  • Patient affiliated to a social security scheme.

You may not qualify if:

  • Patient currently taking corticosteroids or antibiotics or antihistamines or Nonsteroidal anti-inflammatory drugs (NSAIDs) or topical decongestants or systemic decongestants
  • Patient currently using other nasal sprays, nasal pumps, nasal irrigation/lavage device, or oils, creams or gels into the nose.
  • Patient deprived of freedom or subject to legal protection measures.
  • Pregnant or breastfeeding woman.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Pharmacie Lair

Vire, Normandy, 14500, France

RECRUITING

Pharmacie Plaisance

Paris, 75014, France

RECRUITING

MeSH Terms

Conditions

Nasal ObstructionEpistaxisSneezing

Condition Hierarchy (Ancestors)

Nose DiseasesRespiratory Tract DiseasesAirway ObstructionRespiratory InsufficiencyRespiration DisordersOtorhinolaryngologic DiseasesHemorrhagePathologic ProcessesPathological Conditions, Signs and SymptomsSigns and Symptoms, RespiratorySigns and Symptoms

Central Study Contacts

Timothé GOUDOT, Pharmacist

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 6, 2022

First Posted

August 12, 2022

Study Start

September 2, 2022

Primary Completion

October 1, 2023

Study Completion

December 1, 2023

Last Updated

March 3, 2023

Record last verified: 2022-07

Locations