Neuromodulation and Fatigue
Neuromodulation and Its Effects on Muscle Activity and Fatigue
1 other identifier
interventional
40
1 country
1
Brief Summary
In this project, we aim to determine any potential effects of a weak electrical current applied to the neck or thoracic area on functional capacity and muscle activation. Healthy individuals will participate in one familiarization followed by up to 6 experimental sessions. Fatigability and motor function will be assessed in each test session.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jun 2023
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 2, 2022
CompletedFirst Posted
Study publicly available on registry
August 4, 2022
CompletedStudy Start
First participant enrolled
June 3, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 1, 2027
April 9, 2026
April 1, 2026
4.2 years
August 2, 2022
April 3, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Force
Change in force will be evaluated with a device during each test session
Each session will take approximately 2 hours (total of 4 test sessions)
Perception of effort
Change in perceived effort will be evaluated with visual analogue scales
Each session will take approximately 2 hours (total of 4 test sessions)
Muscle activation
Electromyography will be used to quantify muscle activation
Each session will take approximately 2 hours (total of 4 test sessions)
Study Arms (2)
Men
EXPERIMENTALIndividuals will participate in 1 familiarization and up to 6 test sessions
Women
EXPERIMENTALIndividuals will participate in 1 familiarization and up to 6 test sessions
Interventions
different types of low-intensity (comfortable) electrical stimulation will be used and applied in distinct locations
Eligibility Criteria
You may qualify if:
- Healthy individuals between 18 and 50 years old
You may not qualify if:
- Metal implants or joint replacement. Presence of neuromuscular disease. Skin hypersensitivity.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Oklahoma
Norman, Oklahoma, 73071, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Hugo Pereira, PhD
University of Oklahoma
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- BASIC SCIENCE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 2, 2022
First Posted
August 4, 2022
Study Start
June 3, 2023
Primary Completion (Estimated)
September 1, 2027
Study Completion (Estimated)
December 1, 2027
Last Updated
April 9, 2026
Record last verified: 2026-04
Data Sharing
- IPD Sharing
- Will not share