NCT05484388

Brief Summary

The aim of this interventional but non-invasive, clinical investigation is to demonstrate the performance and safety of two new class I medical device Absorbing Hygiene Products developed by Essity. The primary objective is to demonstrate for each of the new products that they provide protection to leakages similar to their corresponding standard of care devices already used on the market. The target population for this clinical investigation are community living individuals suffering from moderate to severe incontinence, who may receive care by a care giving relative, by one or more caregivers and are current users of TENA Pants of the respective absorption level.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
84

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 15, 2022

Completed
2 months until next milestone

First Posted

Study publicly available on registry

August 2, 2022

Completed
2 months until next milestone

Study Start

First participant enrolled

October 3, 2022

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 7, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 3, 2023

Completed
Last Updated

February 21, 2023

Status Verified

February 1, 2023

Enrollment Period

2 months

First QC Date

June 15, 2022

Last Update Submit

February 20, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Reported number of urinary leakages

    The proportion of products experiencing urine leakage over the 10 day test period is compared between the investigational and reference product. Labels are used to collect this information for each used product

    20 days

Secondary Outcomes (3)

  • Incidence of safety events

    20 days

  • Product Satisfaction questionnaire

    20 days

  • Skin health questionnaire

    20 days

Study Arms (4)

SN2

EXPERIMENTAL

new absorbing hygiene product with absorption level Normal.

Device: SN2

SP3

EXPERIMENTAL

new absorbing hygiene product with absorption level Plus.

Device: SP3

TENA Proskin Pants Normal

OTHER

Reference product currently used by the participant (control for SN2).

Device: SN2

TENA Pants Original Plus

OTHER

Reference product currently used by the participant (control for SP3).

Device: SP3

Interventions

SN2DEVICE

Investigational device absorption level Normal

SN2TENA Proskin Pants Normal
SP3DEVICE

Investigational device absorption level Plus

SP3TENA Pants Original Plus

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • criteria to be eligible for this clinical investigation:
  • Subject is diagnosed with moderate to severe urinary incontinence managed only with TENA Pants absorbent hygiene products of size Medium or Large with the same absorption level that is used in the study since at least 4 weeks.
  • Subject is living at home and should have a care giving relative supported by a professional caregiver giver to manage daily activities and incontinence related tasks.
  • Subject is willing and able to provide informed consent and to participate in the clinical investigation or has a legally designated representative willing to provide informed consent on behalf of the subject.
  • Care giving relative is willing and able to provide informed consent to participate in the clinical investigation.
  • If incontinence is managed by pharmaceuticals, the dose regime is stable.
  • Subject and care giving relative (if any) are over 18 years of age.
  • Post-menopausal women or no longer of child-bearing potential

You may not qualify if:

  • Subject is cared for in a professional establishment or is institutionalized.
  • Subject has severe incontinence product related skin problems corresponding to scores equal to or higher than 4 in the skin health assessment, as judged by the investigator.
  • Subject suffers from regular faecal incontinence more than once a week.
  • Subject has any type of urinary catheter(s) resulting in improved/treated urinary incontinence.
  • Any other condition that may make participation in the clinical investigation inappropriate, as judged by investigator.
  • Subject or care giving relative is incapable or unwilling to collect used products and fill out the bag label required for the clinical investigation.
  • Participation in another investigational study of a drug, biologic, or medical device within 30 days prior to entering the clinical investigation or planned during the clinical investigation as well as prior participation in this investigation
  • Subject is pregnant or nursing or of childbearing potential.
  • Investigator suspects that subject or care giving relative has an alcohol or drug addiction.
  • Subject and/or caregiving relative is closely affiliated with or in hierarchical dependency of the Sponsor, PI, or CRO involved in this study
  • Subject's incontinence is currently managed by more than 1 type of AHP's

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Diakonissen-Stiftungs-Krankenhaus Speyer

Speyer, D- 67346, Germany

Location

MeSH Terms

Conditions

Urinary Incontinence

Condition Hierarchy (Ancestors)

Urination DisordersUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesLower Urinary Tract SymptomsUrological ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Kilian Pankert, MD

    Diakonissen-Stiftungs-Krankenhaus Speyer

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Model Details: This is a prospective, randomized pre-market feasibility clinical investigation designed to evaluate the clinical performance and safety of the investigational product in its intended target population. The clinical investigation is designed according to the ISO 14155:2020 as follows: Prospective. Randomized cross-over. Interventional but non-invasive. Decentralized in a home-care environment. A pairwise comparative study.
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 15, 2022

First Posted

August 2, 2022

Study Start

October 3, 2022

Primary Completion

December 7, 2022

Study Completion

February 3, 2023

Last Updated

February 21, 2023

Record last verified: 2023-02

Data Sharing

IPD Sharing
Will not share

Locations