NCT05478850

Brief Summary

In prospective, observational cohort study, changes in body temperature will be investigated before the procedure and during recovery in Radiotherapy patients aged 0-18 years who need sedation due to childhood malignancies. The aims of this study were to measure the incidence and magnitude of changes in body temperature in children undergoing sedation or general anesthesia for Radiotherapy, and to determine their effects on the recovery process.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
152

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Aug 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 25, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 28, 2022

Completed
4 days until next milestone

Study Start

First participant enrolled

August 1, 2022

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2022

Completed
Last Updated

October 13, 2022

Status Verified

July 1, 2022

Enrollment Period

1 month

First QC Date

July 25, 2022

Last Update Submit

October 9, 2022

Conditions

Keywords

Hypothermia; AnesthesiaHyperthermia, Anesthesia RelatedRadiotherapy Side EffectChildhood Cancer

Outcome Measures

Primary Outcomes (2)

  • body temperature change among 2 time period

    non-contact body temperature measured on forehead

    time from before radiotherapy to the end of radiotherapy

  • recovery time from anesthesia

    Time from the end of the procedure until the Modified Steward score ≥ 8 in the patient recovery room

    the time from end of radiotherapy to discharging

Study Arms (1)

Radiotherapy under anesthesia

Procedure: radiotherapy under anesthesia

Interventions

Body temperature change will be investigated before the procedure and during recovery in Radiotherapy patients who need anesthesia due to childhood malignancies.

Radiotherapy under anesthesia

Eligibility Criteria

Age1 Month - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

patients undergoing radiotherapy under anesthesia

You may qualify if:

  • patients undergoing radiotherapy under anesthesia

You may not qualify if:

  • family refusal to participate,
  • chronic nausea and vomiting complaints,
  • active infection,
  • apnea history,
  • cardiac disease, kidney and liver failure,
  • anomalies that may cause difficult airway,
  • metabolic diseases,
  • neurological or muscular diseases.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ankara City Hospital

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

HypothermiaMalignant HyperthermiaRadiation InjuriesNeoplasms

Condition Hierarchy (Ancestors)

Body Temperature ChangesSigns and SymptomsPathological Conditions, Signs and SymptomsIntraoperative ComplicationsPathologic ProcessesPostoperative ComplicationsHyperthermiaWounds and Injuries

Study Officials

  • Betül Güven Aytaç, MD

    Ankara City Hospital Bilkent

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle Investigator

Study Record Dates

First Submitted

July 25, 2022

First Posted

July 28, 2022

Study Start

August 1, 2022

Primary Completion

September 1, 2022

Study Completion

October 1, 2022

Last Updated

October 13, 2022

Record last verified: 2022-07

Locations