Predictors of Pain Chronicity in Patients With Gunshot and Mine-explosive Wounds

NCT05478668 | Completed

• 1 other identifier: №158, 2022.23.05
• Study Type: observational
• Target: 2,215
• Locations: 1 country
• Sites: 1

Brief Summary

82.1% of patients with gunshot and mine-explosive wounds during hostilities in Ukraine have negative results of pain treatment, which leads to its chronicity. Identifying predictors of pain chronicity in these patients may improve their treatment outcomes.

Conditions

Chronic Pain, Widespread

Keywords

Chronic pain, gunshot wounds, mine-explosive wounds

Outcome Measures

Primary Outcomes (5)

• visual analog scale

  evaluation of the number of points

  1 year

• Didier Bouhassiraa DN4

  evaluation of the number of points

  1 year

• The Hospital Anxiety and Depression Scale

  evaluation of the number of points

  1 year

• Chaban Quality of Life Scale

  evaluation of the number of points

  1 year

• Mississippi PTSD scale (military version)

  evaluation of the number of points

  1 year

Study Arms (2)

retrospective analysis

A retrospective analysis of disease histories for the period from 2014 to 2021 was carried out. Data collection was carried out at all stages of treatment: medical and nursing brigade, military mobile hospital, military medical clinical center, during rehabilitation, within 12 months of the injury. In all patients, the assessment of anesthetic risk was carried out according to the ASA scale. The basic tool for pain intensity research was a visual analog scale. Intervals between analgesia were also studied. The study of the neuropathic component of pain was carried out using the Didier Bouhassiraa neuropathic pain diagnostic questionnaire. Study of the presence of an acute stress reaction scale The Hospital Anxiety and Depression Scale. Research on the presence of post-traumatic stress disorders was carried out using the Mississippi scale of post-traumatic stress disorders (military version). Satisfaction with treatment results was studied using the Chaban Quality of Life Scale.

Other: visual analog scale

prospective study

Recruitment of patients for the prospective study was carried out in the period from 02.24.2022 to 05.24.2022. Data collection was carried out during the Russian invasion of Ukraine and the offensive on Kyiv. All patients with gunshot wounds were evacuated to the stage of treatment - the National Military Medical Clinical Center "Main Military Clinical Hospital". The research was conducted using the same methods as during the retrospective analysis. The exception was the study period during treatment at the military medical clinical center: here it was 14 days.

Other: visual analog scale

Interventions

visual analog scale OTHER

In all patients, the assessment of anesthetic risk was carried out according to the ASA scale. The basic tool for pain intensity research was a visual analog scale. Intervals between analgesia were also studied. The study of the neuropathic component of pain was carried out using the Didier Bouhassiraa neuropathic pain diagnostic questionnaire. Study of the presence of an acute stress reaction The Hospital Anxiety and Depression Scale. Research on the presence of post-traumatic stress disorders was carried out using the Mississippi scale of post-traumatic stress disorders (military version). Satisfaction with treatment results was studied using the Chaban Quality of Life Scale.

Also known as: neuropathic pain Didier Bouhassiraa, Nadine Attala et al. Pain, 2005, 114: 29-36 (DN4)., Chaban Quality of Life Scale, The Hospital Anxiety and Depression Scale, Mississippi scale of post-traumatic stress disorders (military version) (MS PTSD (m))

prospective study; retrospective analysis

Eligibility Criteria

• Sex: male
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study was carried out on the basis of the National Military Medical Clinical Center "Main Military Clinical Hospital". All patients participated in Operation Joint Forces and received gunshot wounds during combat operations. A retrospective analysis of disease histories for the period from 2014 to 2021 was carried out. Data collection was carried out at all stages of treatment: medical and nursing brigade, military mobile hospital, military medical clinical center, during rehabilitation, within 12 months of the injury. Recruitment of patients for the prospective study was carried out in the period from 02.24.2022 to 05.24.2022. Data collection was carried out during the Russian invasion of Ukraine and the offensive on Kyiv.

You may qualify if:

• the presence of gunshot and mine-explosive injuries

You may not qualify if:

• absence of gunshot and mine-explosive injuries

Sponsors & Collaborators

• Bogomolets National Medical University: lead

Study Sites (1)

Bogomolets National Medical University, Ministry of Health of Ukraine

Kyiv, Ukraine

Location

MeSH Terms

Conditions

Chronic Pain; Wounds, Gunshot

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Wounds, Penetrating; Wounds and Injuries

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Target Duration: 12 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: I am obtaining the scientific degree of Doctor of Medical Sciences at the Department of Surgery, Anesthesiology and Intensive Care

Study Record Dates

• First Submitted: July 26, 2022
• First Posted: July 28, 2022
• Study Start: February 24, 2022
• Primary Completion: May 24, 2022
• Study Completion: May 24, 2022
• Last Updated: August 2, 2022

Record last verified: 2022-07

Locations

UA (1)