Role of MSCT of Chest in Differentiation Between COPD Patients According to Their Smoking Status

NCT05475977 | Unknown DMC

• 1 other identifier: Somaia Ahmad
• Study Type: observational
• Target: 90
• Locations: 0 countries
• Sites: N/A

Brief Summary

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality all over the world. Smoking is considered as an important risk factor, but other risk factors are present. Around 30 % of patients with COPD are non-smokers. Cessation of smoking in patients with COPD causes decreases the presence of micronodules and other criteria of CT chest. In last few years, some researchers reported that cessation of smoking raise the apparent extent of emphysema. The cause is not obvious, but this paradoxical fall in lung density is thaught to be resulting from decrease in inflammation after smoking cessation. CT chest criteria of COPD in active smokers, non-smokers and ex-smokers seem to be different. So, comparison between CT chest Criteria of COPD in smokers, ex-smokers and non-smokers will be searched in this study to detect the role of multislice computed tomography (MSCT) chest in differentiation between COPD patients according to their smoking status.

Conditions

Patient Participation

Outcome Measures

Primary Outcomes (1)

• Number of participants with criteria of severe COPD

  Criteria of severe COPD include emphysematous bullae, thick bronchial walls.

  18 months

Study Arms (3)

First Group

Thirty patients of COPD smokers patients.

Diagnostic Test: MSCT chest

Second group

Thirty patients of COPD ex-smokers patients.

Diagnostic Test: MSCT chest

Third group

Thirty patients of COPD non-smokers patients.

Diagnostic Test: MSCT chest

Interventions

MSCT chest DIAGNOSTIC_TEST

Multi slice Computed Tomography of the chest

First Group; Second group; Third group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

COPD patients either smokers, ex-smokers or non-smokers

You may qualify if:

• All patients with chronic obstructive Pulmonary Disease.
• Patients above 18 years.

You may not qualify if:

• Patients with unclear smoking history.
• Patients with active pneumonia.
• Patients with acute COPD exacerbation.

Sponsors & Collaborators

• Somaia Ahmad AbdAllah Ahmad: lead

MeSH Terms

Conditions

Patient Participation

Condition Hierarchy (Ancestors)

Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior

Study Officials

• Somaia Ahmad AbdAllah Ahmad, M.B.B.Ch

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Somaia Ahmad AbdAllah Ahmad, M.B.B.Ch

CONTACT

01024833938; somayaahmad64@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Main investigator

Study Record Dates

• First Submitted: June 28, 2022
• First Posted: July 27, 2022
• Study Start: August 1, 2022
• Primary Completion: April 1, 2023
• Study Completion: July 1, 2023
• Last Updated: August 2, 2022

Record last verified: 2022-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR
• Time Frame: 2 years
• Access Criteria: Medical researchers