NCT05473936

Brief Summary

The objective of this study is to compare the results of a COVID-19 specific curriculum led by LACDHS Community Health Workers (CHWs) from these same communities of safety-net patients to effectively increase COVID-19 testing and vaccination for individual patients, and to facilitate needed healthcare in a timely manner for the safety net health system, and to develop a sustained public health presence in these communities to build trust and preparedness for critical COVID-19 related future needs.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
66

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 22, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 26, 2022

Completed
3 months until next milestone

Study Start

First participant enrolled

October 11, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2023

Completed
Last Updated

March 2, 2023

Status Verified

February 1, 2023

Enrollment Period

5 months

First QC Date

July 22, 2022

Last Update Submit

February 28, 2023

Conditions

Keywords

COVID-19 vaccine hesitancyCOVID-19 testingCommunity Health WorkersSafety-Net Patients

Outcome Measures

Primary Outcomes (3)

  • Project Survey: Phenx toolkit - Worry about COVID

    In a 4-point Likert scale, we will ask questions about their worry and concern about getting infected with COVID from "extremely concerned, somewhat concerned, neutral, not concerned" Measure three key measures: trust, self-efficacy, and intent to participate in COVID-19 testing and vaccination. Consolidated pre- and post- surveys (Name: Project Survey) will measure participants' intentions of getting vaccinated and tested for COVID-19.

    Six weeks from start of project

  • Project Survey: Phenx toolkit - Attitudes and Behavior

    In a 5 point Likert scale, questions will ask about attitudes, and behaviors regarding COVID, from "very likely, somewhat likely, neutral, somewhat unlikely, and very unlikely" Measure three key measures: trust, self-efficacy, and intent to participate in COVID-19 testing and vaccination. Consolidated pre- and post- surveys (Name: Project Survey) will measure participants' intentions of getting vaccinated and tested for COVID-19.

    Six weeks from start of project

  • Project Survey: Phenx toolkit - Perceived Coronavirus Threat

    In a 4-point Likert scale, we will ask questions about their perceived Coronavirus threat "extremely concerned, somewhat concerned, neutral, not concerned" Measure three key measures: trust, self-efficacy, and intent to participate in COVID-19 testing and vaccination. Consolidated pre- and post- surveys (Name: Project Survey) will measure participants' intentions of getting vaccinated and tested for COVID-19.

    Six weeks from start of project

Secondary Outcomes (3)

  • Project Survey: Phenx toolkit - Intent to participate in COVID testing and vaccination

    Six weeks from start of project

  • Pre and Post Program Survey: Medical Mistrust Scale

    Six weeks from start of project

  • Sherer, et al.'s General Self-Efficacy Scale

    Six weeks from start of project

Study Arms (2)

Control Arm - Standard Treatment (Group 1)

NO INTERVENTION

The standard care for the control arm will be: the LACDHS Vaccine Hesitancy Outreach Group calling patients once every month to remind patients of the need to be vaccinated and tested if needed. During the duration of the six weeks, the study participants will be exposed to the call from the LACDHS Vaccine Hesitancy Outreach Group. Participants will receive two phone calls six-weeks apart, where they will complete a pre-survey in the first phone call, and 2 surveys (post-survey and CDE survey) in the second phone call. The survey will measure their trust in medical institutions, rate their self-efficacy, and intention, knowledge, and perceptions on COVID-19 testing and vaccination.

Intervention Arm - CHW-led curriculum (Group 2)

EXPERIMENTAL

Participants assigned to the intervention group will complete the same activities as Group 1 and be asked to participate in the virtual intervention, consisting of six-weekly group classes via Zoom, and six-weekly personalized teleconsultations (via phone call or Zoom) at a suitable time for both participants and CHWs. Study participants will receive 6 linguistically and ethnically concordant weekly two-hour group classes and personalized teleconsultations led by CHWs. The total time commitment for Group 2 will be a maximum of 20 hours (6 two-hour group classes, + 6 one hour personal session, + 2 half hour phone calls), over the next 6 weeks.

Behavioral: Community Health Worker led curriculum

Interventions

The intervention arm will consist of a CHW-based health educational program via Zoom, where participants will be provided with information about COVID-19, COVID-19 resources and services in Los Angeles County, and engagement with Los Angeles County Department of Health Services CHWs who will lead the curriculum and be available to answer questions of the intervention arm patients.

Intervention Arm - CHW-led curriculum (Group 2)

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Age 16 years and older
  • Self-identify as African American or Latinx
  • English Speaking
  • Receives primary or specialty care treatment at an LACDHS facility
  • Has either not completed lab orders for COVID-19 testing and/or vaccination at an LACDHS facility
  • Have reliable internet access

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Los Angeles Department of Public Health

Los Angeles, California, 90012, United States

RECRUITING

Charles Drew University of Medicine and Science

Los Angeles, California, 90059, United States

RECRUITING

MeSH Terms

Conditions

Vaccination Hesitancy

Condition Hierarchy (Ancestors)

Vaccination RefusalTreatment RefusalTreatment Adherence and ComplianceHealth BehaviorBehavior

Study Officials

  • Sheba George, PhD

    Charles Drew University of Medicine and Science

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Junko Nishitani, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 22, 2022

First Posted

July 26, 2022

Study Start

October 11, 2022

Primary Completion

March 1, 2023

Study Completion

May 1, 2023

Last Updated

March 2, 2023

Record last verified: 2023-02

Data Sharing

IPD Sharing
Will share

The study falls is managed through the RADxUP program and such it is required for supplement grant projects to share their data dictionaries to the RADx Data Hub.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
The data will become available at the end of study and will be uploaded to the RADxUP Data Hub, managed by Duke Coordinating Center
Access Criteria
Only authorized RADxUP personnel will be able to access the IPD. The link below details how the COVID RADx Data Hub is a centralized, secure repository to store, search for and interrogate vast amounts of de-identified data related to COVID-19 testing and vaccination.
More information

Locations