NCT05466305

Brief Summary

Gold is widely used in prosthetics. Its use ranges from being employed in the fabrication of removable dentures, where the inner surface permanently touching oral cavity tissues, through to fixed dentures, and even some structures of certain implantological systems. All such items can be made of galvanized gold. Thus, new technologies have made gold and its alloys a kind of a universal material.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2022

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 8, 2022

Completed
12 days until next milestone

First Posted

Study publicly available on registry

July 20, 2022

Completed
12 days until next milestone

Study Start

First participant enrolled

August 1, 2022

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2022

Completed
Last Updated

July 21, 2022

Status Verified

July 1, 2022

Enrollment Period

3 months

First QC Date

July 8, 2022

Last Update Submit

July 19, 2022

Conditions

Keywords

GoldChromeDentureMucosa

Outcome Measures

Primary Outcomes (1)

  • Immunological assessment using Salivary IgA level through ELISA test

    Immunological assessment of maxillary complete denture reinforced by gold plated Cr-Co alloy

    45 days

Secondary Outcomes (1)

  • Microbiological assessment using Staphylococcus Aureus, Staphylococcus Epidermis and Candida Albicans Colonization

    45 days

Study Arms (2)

Maxillary complete denture reinforced by chrome cobalt alloy

PLACEBO COMPARATOR

Completely edentulous patients treated by maxillary complete denture reinforced by chrome cobalt alloy

Device: Gold plated chrome cobalt alloy

Maxillary complete denture reinforced by gold plated chrome cobalt alloy

EXPERIMENTAL

Completely edentulous patients treated by maxillary complete denture reinforced by gold plated chrome cobalt alloy

Device: Gold plated chrome cobalt alloy

Interventions

Acrylic resin complete denture having a metal chrome cobalt palatal plate which plated by gold

Also known as: Completely edentulous patients treated by maxillary complete denture reinforced by gold plated chrome cobalt alloy
Maxillary complete denture reinforced by chrome cobalt alloyMaxillary complete denture reinforced by gold plated chrome cobalt alloy

Eligibility Criteria

Age4 Years - 65 Years
Sexmale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Completely edentulous maxillary and mandibular ridges
  • Healthy mucosa and absence of remaining roots
  • Good physical and mental health
  • Willing to give informed consent
  • Normal maxilla-mandibular relationship Angle Class I
  • Adequate bone quality and quantity in terms of width and height in the anterior maxillary mandibular ridges verified by preoperative cone beam CT
  • Adequate inter-arch space to accommodate maxillary and mandibular implant prostheses

You may not qualify if:

  • Uncontrolled diabetes
  • Smoking habits
  • Radiotherapy
  • Clinical or radiographic signs of pathologic conditions
  • Osteoporosis
  • Patients on corticosteroids
  • Bruxism

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Stomatitis, Denture

Condition Hierarchy (Ancestors)

StomatitisMouth DiseasesStomatognathic Diseases

Study Officials

  • Shady M. El Naggar, PhD

    Badr University in Cairo

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Shady M. El Naggar, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Professor

Study Record Dates

First Submitted

July 8, 2022

First Posted

July 20, 2022

Study Start

August 1, 2022

Primary Completion

November 1, 2022

Study Completion

December 1, 2022

Last Updated

July 21, 2022

Record last verified: 2022-07

Data Sharing

IPD Sharing
Will not share