Trials Sponsors Conditions Drugs Pricing

Conditions

Hip Fractures Knee Fracture

Outcome Measures

Primary Outcomes (1)

EuroQual - 5 Dimensions (EQ5D)
quality of life
2013-17

Study Arms (1)

Patients experiencing adverse event while in hospital

Patients that have experienced a patient safety incident according to the Patient Safety Indicators (PSIs) developed by the U.S. Agency for Healthcare Research and Quality (AHRQ)

Procedure: Surgery for hip and knee replacement

Interventions

Surgery for hip and knee replacementProcedure

Elective inpatient surgery for hip and knee replacement

Patients experiencing adverse event while in hospital

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Sexall

Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

The data available for our study was collected between 2013 and 2017. The patient safety incidents studied are relatively rare, and in order to yield enough observations to reliably estimate the impact of different incidents, the sample is limited to patients undergoing hip or knee replacements because these have more observations than do varicose veins and groin hernia. There are 267,477 and 288,967 observations for patients undergoing hip replacement and knee replacement respectively. Furthermore, the sample is limited to patients with observations of health status both before and after surgery.

You may not qualify if:

Patients for which health related quality of life is not observed both before and after surgery.

Sponsors & Collaborators

Imperial College London
Otherlead

Study Sites (1)

Acute Trusts in England

Multiple Locations, United Kingdom

Related Publications (1)

Xiao M, Kristensen SR, Marti J, Mossialos E. The impact of patient safety incidents during hip and knee replacements on patients' health related quality of life: a before and after study using longitudinal data linked to patient-reported outcome measures. Int J Surg. 2023 May 1;109(5):1085-1093. doi: 10.1097/JS9.0000000000000275.
PMID: 37026831DERIVED

MeSH Terms

Conditions

Hip FracturesKnee Fractures

Interventions

Surgical Procedures, OperativePapaverineArthroplasty, Replacement, Knee

Condition Hierarchy (Ancestors)

Femoral FracturesFractures, BoneWounds and InjuriesHip InjuriesLeg InjuriesKnee Injuries

Intervention Hierarchy (Ancestors)

BenzylisoquinolinesAlkaloids

Enrollment

395,346 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: OTHER
Time Perspective: RETROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

July 15, 2022

First Posted

July 19, 2022

Study Start

December 1, 2018

Actual (reported)

The Impact of Patient Safety Incidents on Patients' Quality of Life

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (1)

Patients experiencing adverse event while in hospital

Interventions

Eligibility Criteria

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (1)

Patients experiencing adverse event while in hospital

Interventions

Eligibility Criteria

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

Source record

Locations