Distal Radial Access for Primary PCI in STEMI Patients to Prevent RAO
RAPIDIII
1 other identifier
interventional
512
1 country
1
Brief Summary
Randomized-controlled trial to compare early radial artery occlusion via distal vs. conventional transradial access among ST segment elevation myocardial infarction patients for primary percutaneous coronary intervention.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jan 2022
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 5, 2022
CompletedFirst Submitted
Initial submission to the registry
July 14, 2022
CompletedFirst Posted
Study publicly available on registry
July 18, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 30, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
August 30, 2023
CompletedMarch 11, 2025
March 1, 2025
1.6 years
July 14, 2022
March 7, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
radial artery occlusion
The radial artery occlusion will be evaluated 24 hours after procedure by ultrasound.
at 24 hours after procedure
Secondary Outcomes (10)
the rate of successful puncture
Immediately post-procedurally
puncture time
Immediately post-procedurally
first medical contact to device (FMC2D) time
Immediately post-procedurally
procedural time
Immediately post-procedurally
hemostasis time
at 24 hours after procedure
- +5 more secondary outcomes
Study Arms (2)
distal radial access
EXPERIMENTALDistal radial access for primary percutaneous coronary intervention in STEMI patients
conventional transradial access
ACTIVE COMPARATORconventional transradial access for primary percutaneous coronary intervention in STEMI patients
Interventions
primary percutaneous coronary intervention via distal radial access
primary percutaneous coronary intervention via conventional transradial access
Eligibility Criteria
You may qualify if:
- Age ≥ 18 years
- ST-segment elevation myocardial infarction for primary percuteous coronary intervention
- Palpable pulses on both access sites of the radial artery
- Informed consent
You may not qualify if:
- Thrombolysis before primary percutaneous coronary intervention
- Previous CABG or radio-cephalic fistula using radial artery
- Cardiogenic shock
- Severe arrhythmias
- Severe liver and kidney dysfunction
- Pregnancy
- Enrolment in another study within 1 month
- Inability to obtain written informed consent
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Beijing Luhe hospital
Beijing, Beijing Municipality, 101149, China
Related Publications (1)
Li Z, Wang Y, Song J, Wang S, Wang Y, Wu Y, Wang H, Liu Z, Yan R, Zhai G, Guo J. Distal radial access to prevent radial artery occlusion for STEMI patients (RAPID III): a randomized controlled trial. BMC Med. 2025 Mar 24;23(1):173. doi: 10.1186/s12916-025-04005-1.
PMID: 40128873DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Jincheng Guo
Beijing Luhe Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 14, 2022
First Posted
July 18, 2022
Study Start
January 5, 2022
Primary Completion
August 30, 2023
Study Completion
August 30, 2023
Last Updated
March 11, 2025
Record last verified: 2025-03