NCT05455307

Brief Summary

To conduct a prospective, multi-center study to observe the long-term efficacy and safety of self expanding ureteral stent for treating participants with refractory ureteral stricture.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
15mo left

Started Jul 2022

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress75%
Jul 2022Jul 2027

First Submitted

Initial submission to the registry

June 8, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

July 13, 2022

Completed
17 days until next milestone

Study Start

First participant enrolled

July 30, 2022

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2024

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2027

Expected
Last Updated

July 13, 2022

Status Verified

July 1, 2022

Enrollment Period

2 years

First QC Date

June 8, 2022

Last Update Submit

July 7, 2022

Conditions

Keywords

ureteral stoneureteral stricturehydronephrosis

Outcome Measures

Primary Outcomes (1)

  • Renal function test

    serum creatinine (mg/dL)

    6 months, 12 months, 18 months, 24 months, 30 months, 36 months, 42 months, 48 months, 54 months and 60 months

Secondary Outcomes (2)

  • Complications

    6 months, 12 months, 18 months, 24 months, 30 months, 36 months, 42 months, 48 months, 54 months and 60 months

  • Renal structure

    6 months, 12 months, 18 months, 24 months, 30 months, 36 months, 42 months, 48 months, 54 months and 60 months

Study Arms (1)

single arm

EXPERIMENTAL

single arm without placebo control

Device: Allium ureteral stent

Interventions

observe the effficacy and safety of long-term self expanding ureteral stents for treating refractory ureteral stricture

single arm

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • refractory ureteral stricture after at least two times of ureteral dilation

You may not qualify if:

  • poor cardiovascular function for anesthesia unwilling to accept the long-term placement of ureteral stent uncontrolled urinary tract infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

En Chu Kong Hospital

New Taipei City, 23702, Taiwan

RECRUITING

Related Publications (2)

  • Avitan O, Bahouth Z, Shprits S, Gorenberg M, Halachmi S. Allium Ureteral Stent as a Treatment for Ureteral Stricture: Results and Concerns. Urol Int. 2022;106(5):482-486. doi: 10.1159/000522174. Epub 2022 Mar 1.

  • Sampogna G, Grasso A, Montanari E. Expandable metallic ureteral stent: indications and results. Minerva Urol Nefrol. 2018 Jun;70(3):275-285. doi: 10.23736/S0393-2249.18.03035-7. Epub 2018 Mar 28.

MeSH Terms

Conditions

HydronephrosisUreterolithiasis

Condition Hierarchy (Ancestors)

Kidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesUreteral DiseasesUrolithiasis

Study Officials

  • Chung Cheng Wang, MD PhD

    En Chu Kong Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Chung Cheng Wang, MD PhD

CONTACT

Hsin-Yi Lin, BS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Masking Details
no masking
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: single group without control
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chief of department of Urology

Study Record Dates

First Submitted

June 8, 2022

First Posted

July 13, 2022

Study Start

July 30, 2022

Primary Completion

July 30, 2024

Study Completion (Estimated)

July 30, 2027

Last Updated

July 13, 2022

Record last verified: 2022-07

Data Sharing

IPD Sharing
Will not share

Other researchers can e-mail to us for data sharing

Locations