Effect of Aquatic Exercise and Traditional Physical Therapy on Gout in Hypertensive Menopausal Women With Hyperuricemia

NCT05454423 | Unknown

• 1 other identifier: A Eon gout
• Study Type: interventional
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Aquatic Exercise and traditional physical therapy are effective methods of treatment for gout and hypertension in menopausal women.

Conditions

Gout

Outcome Measures

Primary Outcomes (4)

• Serum uric acid level before and after treatment for both groups (A and B): Table 2: Mean values for Serum uric acid level before and after treatment for both groups (A and B).

  a sample of blood was used to assess the level of uric acid in the blood for both groups A \& B before and after treatment

  2 week before and 2 week after

• Visual analogue scale before and after treatment for both groups (A and B): Chicago, Illinois, USA). The P-value is the degree of significance. A P value less than or equal to 0.05 was considered to be significant.

  consists of a straight line with the endpoints defining extreme limits such as 'no pain at all' and 'pain as bad as it could be. The patient was asked to mark her pain level on the line between the two endpoints. The distance between 'no pain at all' and the mark then defines the subject's pain intensity .

  2 week before and 2 week after

• The Borg Rating of Perceived Exertion (RPE) scale

  will be used to measure the level of exertional effort for both groups A \& B before and after treatment

  2 week before and 2 week after

• Digital blood pressure monitor

  It measures blood pressure (systolic \& diastolic) quickly, is easy to use, reliable, and convenient to carry. The monitor has a display that shows systolic blood pressure and diastolic blood pressure. The machine comes with an arm cuff with an air tube and an air jack for connecting the cuff to the machine

  2 week before and 2 week after

Study Arms (2)

aquatic exercise + Traditional physical therapy + anti-hyperuricemia medication

EXPERIMENTAL

consisted of 50 Patients received aquatic exercise and Traditional physical therapy in addition to anti-hyperuricemia medication (a potent purine xanthine oxidase (XO) inhibitor) in therapeutic dose.

Other: the Aquatic exercises +Traditional physical therapy programs +anti-hyperuricemia medication

traditional physical therapy + anti-hyperuricemia medication

PLACEBO COMPARATOR

consisted of 50 Patients received traditional physical therapy in addition to anti-hyperuricemia medication (a potent purine xanthine oxidase (XO) inhibitor) in therapeutic dose.

Other: traditional physical therapy + anti-hyperuricemia medication

Interventions

the Aquatic exercises +Traditional physical therapy programs +anti-hyperuricemia medication OTHER

-Aquatic exercises: At the beginning of the exercises, aquatic exercises technique was educated to the participants out of water. Then, the aquatic exercises were conducted in a chest warm pool (28-30°C) for 30 minutes, three sessions a week for eight weeks. -Traditional physical therapy programs : which included using hot packs (20 minutes), ultrasound (5 minutes), and electrotherapy using TENS (15 minutes) in addition to stretching exercises for the calf, hamstring muscles and big toes and strengthening exercises for the quadriceps muscles for 30 minutes". The stretching exercises were performed in 3 weekly sessions over 8 weeks, each with a 30 second holding and a 30-second relaxation repeated three times. One group of strengthening exercises consisted of 10 repeats with a 5 second holding

aquatic exercise + Traditional physical therapy + anti-hyperuricemia medication

traditional physical therapy + anti-hyperuricemia medication OTHER

traditional physical therapy programs, which included using hot packs (20 minutes), ultrasound (5 minutes), and electrotherapy using TENS (15 minutes) in addition to stretching exercises for the calf, hamstring muscles and big toes and strengthening exercises for the quadriceps muscles for 30 minutes". The stretching exercises were performed in 3 weekly sessions over 8 weeks, each with a 30 second holding and a 30 second relaxation repeated three times. One group of strengthening exercises consisted of 10 repeats with a 5 second holding17.

traditional physical therapy + anti-hyperuricemia medication

Eligibility Criteria

• Age: 45 Years - 65 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• patients with gout
• Age between 45 -65 years
• Cooperative patient.
• A physician referred all patients with the diagnosis of gout

You may not qualify if:

• history of kidney disease such as chronic kidney disease, Cancer patients. Smokers Patients with chronic heart disease.

Sponsors & Collaborators

• Merit University: lead

Related Publications (3)

• Derby CA, Crawford SL, Pasternak RC, Sowers M, Sternfeld B, Matthews KA. Lipid changes during the menopause transition in relation to age and weight: the Study of Women's Health Across the Nation. Am J Epidemiol. 2009 Jun 1;169(11):1352-61. doi: 10.1093/aje/kwp043. Epub 2009 Apr 8.

  PMID: 19357323 BACKGROUND

• Richette P, Bardin T. Gout. Lancet. 2010 Jan 23;375(9711):318-28. doi: 10.1016/S0140-6736(09)60883-7. Epub 2009 Aug 17.

  PMID: 19692116 BACKGROUND

• Dalbeth N, Merriman TR, Stamp LK. Gout. Lancet. 2016 Oct 22;388(10055):2039-2052. doi: 10.1016/S0140-6736(16)00346-9. Epub 2016 Apr 21.

  PMID: 27112094 BACKGROUND

MeSH Terms

Conditions

Gout

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Crystal Arthropathies; Rheumatic Diseases; Purine-Pyrimidine Metabolism, Inborn Errors; Metabolism, Inborn Errors; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Metabolic Diseases; Nutritional and Metabolic Diseases

Central Study Contacts

Ahmed A Abd El Rahim, PHD

CONTACT

01006281510; toota_1234@yahoo.com

Mohamed Mabrouk, PHD

CONTACT

01155555088; Mohamed.hypa@deraya.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Aquatic Exercise and traditional physical therapy are effective methods of treatment for gout and hypertension in menopausal women.

Study Record Dates

• First Submitted: June 29, 2022
• First Posted: July 12, 2022
• Study Start: July 1, 2022
• Primary Completion: August 1, 2023
• Study Completion: September 1, 2023
• Last Updated: July 12, 2022

Record last verified: 2022-07