A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients
1 other identifier
observational
2,000
1 country
34
Brief Summary
Stroke is the leading cause of premature death and disability, and early recognition and treatment of dysphagia is fundamental to stroke management. Early and full tube feeding in the acute phase of stroke helps to address nutritional problems resulting from dysphagia and impaired consciousness and helps to reduce morbidity and mortality and poor outcomes. Current guidelines for acute stroke management do not address the goal of tube feeding of enteral nutrition for energy and protein. In the treatment of acute stroke, there is a strong global focus on pharmacological thrombolysis or mechanical thrombolysis, with nutritional interventions being a less explored topic. Real-world evidence on large samples, feeding attainment and outcomes, and nutrition in the acute phase of stroke is lacking in China . The aim of this study was to understand the current status of nutritional therapy in stroke hospitalization in neurology and its impact on prognosis nationwide, and to improve the standardized management process of enteral nutrition therapy in the acute phase of stroke.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2022
34 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 1, 2022
CompletedFirst Posted
Study publicly available on registry
July 12, 2022
CompletedStudy Start
First participant enrolled
September 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 15, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
October 15, 2023
CompletedJuly 12, 2022
October 1, 2021
1 month
July 1, 2022
July 7, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Nutrition implementation rate
Proportion of patients hospitalized for stroke who were given nutritional support
The first day of admission； the seventh day of admission； the day before discharge.
Nutrition compliance rate of stroke inpatients
Percentage of patients hospitalized for stroke whose nutritional indicators and nutritional status met the guidelines after being given nutritional support
The first day of admission； the seventh day of admission； the day before discharge.
Secondary Outcomes (4)
30-day post-discharge mortality
30-day post-discharge
Infection rate
30-day post-discharge
Readmission rate
30-day post-discharge
Functional prognosis
30-day post-discharge
Study Arms (1)
case group
Patients with acute stroke with nutritional risk
Interventions
Eligibility Criteria
Newly admitted stroke patients admitted to the neurology unit, ≥18 years of age, within 7 days of onset, expected survival \>3 months, expected neurology stay 7-10 days, and at risk of malnutrition (MUST ≥2 points) or at nutritional risk (NRS2002 ≥3 points). Patients' age, sex, hospital, hospitalization number, height, primary diagnosis on admission, and previous underlying disease were collected.
You may qualify if:
- Newly admitted stroke patients admitted to neurology, age ≥18 years, within 7 days of onset, expected survival \>3 months (i.e., not end-stage), expected neurology stay 7-10 days；
- At risk of malnutrition (MUST ≥ 2 points) or at nutritional risk (NRS2002 ≥ 3 points), sign an informed notice.
You may not qualify if:
- Transferred during treatment, contraindications to nutritional therapy (e.g., hemodynamic instability, gastrointestinal bleeding (bleeding \>100 ml), other nutritional studies, pregnancy.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Nanfang Hospital, Southern Medical Universitylead
- First Affiliated Hospital of Fujian Medical Universitycollaborator
- Yantai Yuhuangding Hospitalcollaborator
- The First Hospital of Jilin Universitycollaborator
- Qilu Hospital of Shandong Universitycollaborator
- ZHEJIANG PROVINCE XIAOSHAN HOSPITALcollaborator
- Affiliated Wenling Hospital of Wenzhou Medical Universitycollaborator
- Ganzhou People's Hospitalcollaborator
- Affiliated Hospital of Jining Medical hospitalcollaborator
- Henan Provincial People's Hospitalcollaborator
- Zhongda Hospitalcollaborator
- The Second Affiliated Hospital of Harbin Medical Universitycollaborator
- The First People's Hospital of Kunshancollaborator
- The 2nd Affiliated Hospital of Wenzhou Medical Universitycollaborator
- THE FIRST PEOPLE'S HOSPITAL OF JIASHANcollaborator
- First Affiliated Hospital Xi'an Jiaotong Universitycollaborator
- Fujian Province Zhangzhou Hospitalcollaborator
- People's Hospital of Chongqingcollaborator
- Nanjing Zijin Hospitalcollaborator
- Red Cross Hospital, Hangzhou, Chinacollaborator
- Wenzhou Hospital of Chinese Medicinecollaborator
- Kaifeng Central Hospitalcollaborator
- First Affiliated Hospital of Guangxi Medical Universitycollaborator
- Zhongshan Hospital of Xiamen Universitycollaborator
- Xi'an Encephalopathy of Traditional Chinese Medicine Hospitalcollaborator
- 903 Hospital of Chinese People's Liberation Armycollaborator
- Xiangya Hospital of Central South Universitycollaborator
- Second Affiliated Hospital of Suzhou Universitycollaborator
- Tongji Hospitalcollaborator
- The Affiliated Hospital o fQingdao Universitycollaborator
- The First Affiliated Hospital of Anhui Medical Universitycollaborator
- Yancheng Third People's Hospitalcollaborator
- Linyi People's Hospitalcollaborator
- Dongfang Hospital Beijing University of Chinese Medicinecollaborator
- The Affiliated Hospital of Qingdao Universitycollaborator
Study Sites (34)
The First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, China
Dongfang Hospital of Beijing University of Chinese Medicine
Beijing, Beijing Municipality, China
The First Afilliated Hospital of Fujian Medical University
Fuzhou, Fujian, China
Zhongshan Hospital Xiamen University
Xiamen, Fujian, China
Fujian Province Zhangzhou Hospital
Zhengzhou, Fujian, China
Nanfang Hospital of Southern Medical University
Guangzhou, Guangdong, China
The First Affiliated Hospital of Guangxi Medical University
Nanning, Guangxi, China
The second Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, China
Kaifeng Central Hospital
Kaifeng, Henan, China
Henan Provincial People'S Hospital
Zhengzhou, Henan, China
Tongji Hospital of Tongji Medical College of HUST
Wuhan, Hubei, China
Xiangya Hospital Central South University
Changsha, Hunan, China
The First People'S Hospital of Kunshan
Kunshan, Jiangsu, China
Nanjing Zijin Hospital
Nanjing, Jiangsu, China
Zhongda Hospital Southeast Universtiy
Nanjing, Jiangsu, China
The second Affiliated Hospital of Suzhou University
Suzhou, Jiangsu, China
Yancheng Third People's Hospital
Yancheng, Jiangsu, China
Ganzhou People'S Hospital
Ganzhou, Jiangxi, China
The First Hospital of Jilin University
Changchun, Jilin, China
Qilu Hospital of Shandong University
Jinan, Shandong, China
Affiliated Hospital of Jining Medical Hospital
Jining, Shandong, China
Linyi People'S Hospital
Linyi, Shandong, China
Qilu Hospital of Shandong University(Qingdao)
Qingdao, Shandong, China
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China
Yantai Yuhuangding Hospital
Yantai, Shandong, China
The First Affiliated Hospital of Xi'an Jiaotong University
Xi’an, Shanxi, China
Xi'an Encephalopathy of Traditional Chinese Medicine Hospital
Xi’an, Shanxi, China
Chongqing People's Hospital
Chongqing, Sichuang, China
Red Cross Hospital of Hangzhou
Hangzhou, Zhejiang, China
Zhejiang Province Xiaoshan Hospital
Hanzhou, Zhejiang, China
The First People'S Hospital of Jiashan
Jiaxing, Zhejiang, China
The First People'S Hospital of Wenling
Wenling, Zhejiang, China
The 2nd Affiliated Hospital and Yuying Children's Hospital of WMU
Wenzhou, Zhejiang, China
Wenzhou Hospital of Chinese Medicine
Wenzhou, Zhejiang, China
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Suyue Pan, M.D., Ph.D.
Department of Neurology, Nanfang Hospital, Southern Medical University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 1, 2022
First Posted
July 12, 2022
Study Start
September 1, 2022
Primary Completion
October 15, 2022
Study Completion
October 15, 2023
Last Updated
July 12, 2022
Record last verified: 2021-10
Data Sharing
- IPD Sharing
- Will not share