NCT05452395

Brief Summary

Acute illness could be enormous stress for frail people. Combining comprehensive geriatric assessment and multifactorial intervention has positive effects on frail community older adults. However, few studies investigated the effects of post-acute care (PAC) in frail older patients who just recovered from acute hospitalization. This study aimed to evaluate the effects of PAC on frail older adults in Taiwan.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
254

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 19, 2020

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

July 6, 2022

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 11, 2022

Completed
Last Updated

July 11, 2022

Status Verified

July 1, 2022

Enrollment Period

7 months

First QC Date

July 6, 2022

Last Update Submit

July 6, 2022

Conditions

FrailtyRetrospective Study

Outcome Measures

Primary Outcomes (3)

  • 90-day emergency room visits

    Emergency room visits after post-acute care

    90 days after post-acute care

  • 90-day readmissions

    Readmissions visits after post-acute care

    90 days after post-acute care

  • 90-day mortality

    Mortality after post-acute care

    90 days after post-acute care

Study Arms (2)

Post-acute care

EXPERIMENTAL

comprehensive geriatric assessment, and either home-based or hospital-based post-acute care

Other: Post-acute care

control group

NO INTERVENTION

comprehensive geriatric assessment only

Interventions

Post-acute careOTHER

A personalized care program, focusing on managing geriatric syndromes and improving functional performances. Strength training, activities of daily living (ADL) and instrumental activities of daily living (IADL) practice, basic mobility training, reconditioning exercise, and home environment assessment and modification.

Post-acute care

Eligibility Criteria

Age75 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Mild to severe frailty identified by the Clinical Frailty Scale
  • Age ≥ 75 years
  • Diagnosis with Parkinson's disease, dementia, chronic obstructive pulmonary disease, or chronic kidney disease stage three or worse
  • Acute hospital stays between 3 to 30 days with deconditioning
  • Stable medical condition with no need of intensive care, laboratory examination, or oxygen dependence

You may not qualify if:

  • Refused to participate in the program
  • Candidate for other post-acute care programs (i.e. stroke, traumatic neurological injury, or fracture)
  • Unable to cooperate with the program due to mental or cognitive impairment
  • Long-term ventilator-dependence
  • Long-term bed-ridden status (\> 6 months)
  • Diagnosed as end of life and in need of palliative care
  • Diagnosed as major illness (i.e. end-stage renal disease) and in need of frequent inpatient treatment ( \> 3 times over recent 6 months)
  • Institutional residents
  • Home medical care participants

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Taipei City Hospital

Taipei, Taiwan

Location

Related Publications (1)

  • Lee MC, Wu TY, Huang SJ, Chen YM, Hsiao SH, Tsai CY. Post-acute care for frail older people decreases 90-day emergency room visits, readmissions and mortality: An interventional study. PLoS One. 2023 Jan 6;18(1):e0279654. doi: 10.1371/journal.pone.0279654. eCollection 2023.

    PMID: 36607971DERIVED

MeSH Terms

Conditions

Frailty

Interventions

Subacute Care

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Patient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • Tai-Yin Wu, PhD

    Department of Family Medicine, Taipei City Hospital, Zhongxing Branch

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

July 6, 2022

First Posted

July 11, 2022

Study Start

June 19, 2020

Primary Completion

December 31, 2020

Study Completion

December 31, 2020

Last Updated

July 11, 2022

Record last verified: 2022-07

Locations

TW(1)