Impact of Postoperative Transitional Pain on Recovery After Thoracic Surgery

NCT05450172 | Completed

• 1 other identifier: 49RC22_0203
• Study Type: observational
• Target: 204
• Locations: 1 country
• Sites: 1

Brief Summary

Postoperative transitional pain corresponds to the pain occuring between acute postoperative pain and chronic postsurgical pain (defined as pain persisting for at least 3 months after surgery). We hypothesized that both trajectory and neuropathic component of transitional pain may influence the quality of recovery after thoracic surgery. To test this, we designed an observational study to identify risk factors for incomplete recovery assessed through the QoR-15 questionnaire.

Conditions

Postoperative Recovery

Keywords

Postoperative transitional pain; postoperative pain trajectory; postoperative neuropathic pain; thoracic surgery

Outcome Measures

Primary Outcomes (1)

• Impact of pain trajectory and neuropathic component of pain on quality of recovery.

  An incomplete recovery will be defined as a postoperative QoR-15 score of at least 8 points lower than the preoperative QoR-15 value. The association between both trajectory and neuropathic component of postoperative transitional pain and incomplete recovery will be evaluated.

  3 months after surgery.

Secondary Outcomes (5)

• Description of trajectory and neuropathic component of postoperative transitional pain.

  Between postoperative day 2 and 3 months after surgery.

• Impact of the type of surgery on quality of recovery.

  3 months after surgery.

• Impact of pain trajectory, neuropathic component of pain and type of surgery on chronic postsurgical pain prevalence.

  3 and 6 months after surgery.

• Predictive accuracy of neuropathic pain trajectory on incomplete recovery and chronic postsurgical pain prevalence.

  3 and 6 months after surgery.

• Correlation between neuropathic componente of chronic postsurgical pain and quality of recovery.

  3 and 6 months after surgery.

Study Arms (1)

Consecutive patients scheduled for thoracic surgery

Other: QoR-15 questionnaire

Interventions

QoR-15 questionnaire OTHER

The QoR-15 is a 15-item questionnaire on postoperative quality of recovery. The DN4 is a 10-item questionnaire on neuropathic pain. Both questionnaires will be given to the patients preoperatively, on postoperative days 2 and 3, and 1, 3 and 6 months after surgery.

Also known as: DN4 questionnaire

Consecutive patients scheduled for thoracic surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients scheduled for thoracic surgery (thoracotomy or video-assisted thoracic surgery or surgery for thoracic outlet syndrome).

You may qualify if:

• adult patients
• patients scheduled for thoracic surgery (thoracotomy or video-assisted thoracic surgery or surgery for thoracic outlet syndrome)
• patients who do not object to the study

You may not qualify if:

• patients non francophone
• emergency surgery or revision surgery
• patients already included in the study during the previous 6 months

Sponsors & Collaborators

• University Hospital, Angers: lead

Study Sites (1)

CHU

Angers, 49933, France

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 5, 2022
• First Posted: July 8, 2022
• Study Start: October 10, 2022
• Primary Completion: March 10, 2024
• Study Completion: June 10, 2024
• Last Updated: December 30, 2025

Record last verified: 2025-12

Locations

FR (1)