NCT05449756

Brief Summary

This is a follow-up study of a randomised clinical trial, called TEMPO (a double-blind randomized clinical trial investigating infant formula and human breast milk consumption), in which infants participated in their first year of life. The investigators like to know if these children develop allergies or infections in childhood and whether their feeding pattern in infancy plays a role.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
705

participants targeted

Target at P75+ for all trials

Timeline
35mo left

Started May 2023

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress50%
May 2023Mar 2029

First Submitted

Initial submission to the registry

July 4, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 8, 2022

Completed
11 months until next milestone

Study Start

First participant enrolled

May 30, 2023

Completed
5.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2029

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2029

Last Updated

December 11, 2023

Status Verified

December 1, 2023

Enrollment Period

5.8 years

First QC Date

July 4, 2022

Last Update Submit

December 4, 2023

Conditions

Outcome Measures

Primary Outcomes (3)

  • Parent-reported symptoms of allergies and infections

    The occurrence of parent-reported - symptoms suggestive of allergies and infections

    7.5 years

  • Parent-reported use of medications and/or a medical device

    The occurrence of parent-reported - use of medications and/or a medical device to prevent or relieve symptoms suggestive of allergies and infections

    7.5 years

  • Parent-reported - hospitalisations and visits to the emergency room

    The occurrence of parent-reported - hospitalisations and visits to the emergency room for symptoms suggestive of allergies and infections

    7.5 years

Study Arms (1)

Children who participated in randomised clinical trail, called TEMPO, in their first year of life

Children who participated in randomised clinical trail, called TEMPO, in their first year of life

Other: Self-administered questionnaires

Interventions

Three-monthly self-administered digital questionnaires (accessed on smartphone, tablet or computer)

Children who participated in randomised clinical trail, called TEMPO, in their first year of life

Eligibility Criteria

Age3 Years - 10 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

TEMPO study subjects who completed the final (12 months) visit in the TEMPO study and consented to be approached for follow-up

You may qualify if:

  • Subjects are eligible to participate in the TEMPO Follow-Up study in case:
  • they completed the final (12 months) visit in the TEMPO study.
  • parents agree that their contact details will be shared with a third party for study purposes.
  • parents agree that data collected in the TEMPO study will be used in the TEMPO Follow-Up study.
  • parents provide written informed consent for participation in the TEMPO Follow-Up in accordance with local law.

You may not qualify if:

  • Parents who do not have a smartphone, tablet or personal computer with internet access.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

PreCare Trial & Recruitment

Beek, 6191 JW, Netherlands

RECRUITING

MeSH Terms

Conditions

HypersensitivityInfections

Condition Hierarchy (Ancestors)

Immune System Diseases

Central Study Contacts

Danone Nutricia Research Research

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 4, 2022

First Posted

July 8, 2022

Study Start

May 30, 2023

Primary Completion (Estimated)

March 31, 2029

Study Completion (Estimated)

March 31, 2029

Last Updated

December 11, 2023

Record last verified: 2023-12

Data Sharing

IPD Sharing
Will not share

Locations