NCT05443243

Brief Summary

The objective of this study is to compare the long-term survival as well as the functional and radiographic results of the rods in the alignment of the varus to the stems in the neutral alignment by comparing 2 groups of implanted Total Hip Arthroplasty. 1 group of stems implanted in varus position. 1 group of stems implanted in neutral position

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
210

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 13, 2022

Completed
3 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 16, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 16, 2022

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

May 17, 2022

Completed
2 months until next milestone

First Posted

Study publicly available on registry

July 5, 2022

Completed
Last Updated

July 5, 2022

Status Verified

April 1, 2022

Enrollment Period

3 days

First QC Date

May 17, 2022

Last Update Submit

June 29, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Survival rate

    The main outcome measured was the survival of the implant

    It was measured in October 2021

Secondary Outcomes (11)

  • HHS

    It was measured in October 2021

  • PMA score :

    It was measured in October 2021

  • Thigh pain

    It was measured in October 2021

  • Dislocation

    It was measured in October 2021

  • Hip ROM

    It was measured in October 2021

  • +6 more secondary outcomes

Study Arms (2)

Varus Stems

Patients with a THA Stem implanted in Varus position

Procedure: Total Hip Arthroplasty

Neutral stems

Patients with a THA Stem implanted in Neutral position

Procedure: Total Hip Arthroplasty

Interventions

Patient were operated, a Total hip arthroplasty was performed

Neutral stemsVarus Stems

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients who received a first-line PTH between 2007 and 2012,

You may qualify if:

  • PTH rod implanted in varus,
  • Having X-rays and clinical data in their file
  • Within a period of less than 6 months
  • No opposition

You may not qualify if:

  • PTH in a context of fracture of the femoral neck
  • PTH 2nd intention
  • Lost to sight
  • Patients who died within 6 months
  • Refusal to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU de Brest

Brest, 29609, France

Location

Related Publications (3)

  • Batailler C, Fary C, Servien E, Lustig S. Influence of femoral broach shape on stem alignment using anterior approach for total hip arthroplasty: A radiologic comparative study of 3 different stems. PLoS One. 2018 Oct 5;13(10):e0204591. doi: 10.1371/journal.pone.0204591. eCollection 2018.

  • Murphy CG, Bonnin MP, Desbiolles AH, Carrillon Y, Asmall yi, Ukrainiant Si Selmi T. Varus will have varus; a radiological study to assess and predict varus stem placement in uncemented femoral stems. Hip Int. 2016 Nov 10;26(6):554-560. doi: 10.5301/hipint.5000412. Epub 2016 Oct 15.

  • Fottner A, Woiczinski M, Kistler M, Schroder C, Schmidutz TF, Jansson V, Schmidutz F. Varus malalignment of cementless hip stems provides sufficient primary stability but highly increases distal strain distribution. Clin Biomech (Bristol). 2018 Oct;58:14-20. doi: 10.1016/j.clinbiomech.2018.07.006. Epub 2018 Jul 5.

MeSH Terms

Interventions

Arthroplasty, Replacement, Hip

Intervention Hierarchy (Ancestors)

Arthroplasty, ReplacementArthroplastyOrthopedic ProceduresSurgical Procedures, OperativePlastic Surgery ProceduresProsthesis Implantation

Study Officials

  • Hoel Letissier, MD

    CHU de Brest

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 17, 2022

First Posted

July 5, 2022

Study Start

May 13, 2022

Primary Completion

May 16, 2022

Study Completion

May 16, 2022

Last Updated

July 5, 2022

Record last verified: 2022-04

Locations