Toxicological Analysis in Chemical Submission

NCT05442255 | Completed

• 2 other identifiers: APHP2000542019-A03134-53
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to carry out a systematic toxicological analysis of all the patients, examined at the UMJ of the Hôtel-Dieu following a complaint for suspected chemical submission. By comparing the toxicological data with the clinical examination data (e.g. treatment intake), the investigators could determine the number of confirmed chemical submissions and the substances involved.

Conditions

Chemical Submission

Keywords

Toxicological analysis; chemical submission; psychoactive substances; date rape drug

Outcome Measures

Primary Outcomes (2)

• Presence of one or more psychoactive substances

  Identify the presence of one or more psychoactive substances in the tests performed (blood).

  Day of inclusion

• Presence of one or more psychoactive substances

  Identify the presence of one or more psychoactive substances in the tests performed (urines).

  Day of inclusion

Secondary Outcomes (3)

• Questionnaire

  Day of inclusion

• Quantification of ethanol

  Day of inclusion

• Quantification of ethylglucuronide

  Day of inclusion

Study Arms (1)

Chemical Submission

Patients with a suspected chemical submission

Other: Toxicological analysis

Interventions

Toxicological analysis OTHER

Automated enzymatic assays Automated Immunoassay Urine Screening High Resolution Toxicological Screening

Chemical Submission

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Alleged victims of criminal offences following their filing of a complaint for medical examination on judicial requisition, seen in the Medico-Judicial Unit (UMJ) of the Hôtel-Dieu Hospital in Paris, France.

You may qualify if:

• Be of legal age (≥ 18) on the day of the exam,
• Have filed a complaint for a suspected chemical chemical,
• Be in possession of a judicial requisition requesting the to take biological samples (blood and urine)
• Claim to be the victim of a suspected chemical chemical submission that took place less than 5 days before the consultation,
• Be affiliated or entitled to a social security system,
• Having been informed of the research and not having opposed to his participation.

You may not qualify if:

• Patient under court protection
• Minor patient (\< 18 ans),
• Patient under guardianship,
• Patient who does not speak French,
• Patient with psychotic / cognitive symptoms that may impair their judgment,

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead
• URC-CIC Paris Descartes Necker Cochin: collaborator

Study Sites (1)

Hôtel-Dieu Hospital

Paris, IDF, 75004, France

Location

Related Publications (1)

• Liautard M, Magny R, Houze P, Deguette C, Alcaraz E, Douaouria S, Gorgiard C, Labat L, Dufayet L. Pro-active drug-facilitated crimes (DFC): a study in the Department of Forensic Medicine of Paris, France. Int J Legal Med. 2024 Mar;138(2):415-430. doi: 10.1007/s00414-023-03090-2. Epub 2023 Sep 28.

  PMID: 37768350 BACKGROUND

Study Officials

• DUFAYET Laurène, MD

  Assistance Publique - Hôpitaux de Paris

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 28, 2022
• First Posted: July 1, 2022
• Study Start: March 1, 2021
• Primary Completion: April 15, 2022
• Study Completion: July 27, 2022
• Last Updated: September 12, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)