NCT05432154

Brief Summary

The objective of the study is to determine the efficacy of 7-0940 in the management of atrophic vaginitis in female patients

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2022

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

June 20, 2022

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 27, 2022

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2022

Completed
Last Updated

August 24, 2022

Status Verified

August 1, 2022

Enrollment Period

4 months

First QC Date

June 20, 2022

Last Update Submit

August 23, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Patient-reported Vulvar Quality of Life

    Vulvar Quality of Life Index

    3 months

Secondary Outcomes (3)

  • Patient-reported symptoms

    3 months

  • Severity of overall condition

    3 months

  • Product rating

    3 months

Study Arms (1)

Treatment arm

EXPERIMENTAL

Patients apply 7-0940 at least 2 times daily for 3 months.

Device: Film forming silicone gel (7-0940)

Interventions

Film forming silicone gel (7-0940) is an innovative gel that forms a full contact, flexible wound dressing for supporting mucosal conditions of the genital, rectal and perineal areas. Film forming silicone gel (7-0940) is a semi-occlusive, non-resorbable, self-drying and transparent gel. Film forming silicone gel (7-0940) may be directly applied to dry, wet, cracked and sensitive mucosal tissue. Film forming silicone gel (7-0940) gel is bacteriostatic and inert. It contains no alcohols, parabens or fragrances.

Treatment arm

Eligibility Criteria

Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Able to provide informed consent
  • Diagnosed acute or chronic Atrophic Vaginitis
  • Controlled disease, or uncontrolled disease that did not respond to standard therapy with HRT

You may not qualify if:

  • Unable to provide informed consent
  • Patient unable to apply topical device
  • Allergy or intolerance to ingredients or excipients of the formulation of studied products
  • Currently on HRT (orally or topically)
  • Currently on corticosteroid treatment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Orange Coast Women's Medical Group

Laguna Hills, California, 92653, United States

Location

MeSH Terms

Conditions

Atrophic Vaginitis

Condition Hierarchy (Ancestors)

VaginitisVaginal DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 20, 2022

First Posted

June 27, 2022

Study Start

April 1, 2022

Primary Completion

July 31, 2022

Study Completion

July 31, 2022

Last Updated

August 24, 2022

Record last verified: 2022-08

Data Sharing

IPD Sharing
Will not share

Locations