Laparoscopic Versus Open Appendectomy in Pregnancy
1 other identifier
observational
109
1 country
1
Brief Summary
The aim of this retrospective trial is to compare surgical and pregnancy outcomes of pregnant patients who underwent laparoscopic or open appendectomy for acute appendicitis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Nov 2021
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2022
CompletedFirst Submitted
Initial submission to the registry
June 12, 2022
CompletedFirst Posted
Study publicly available on registry
June 24, 2022
CompletedJune 24, 2022
June 1, 2022
7 months
June 12, 2022
June 18, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Obstetrical outcomes
Pregnancy loss (fetal demise) - rate of cessation of pregnancy before scheduled delivery
Pregnancy loss within 9 months from appendectomy
Secondary Outcomes (1)
Surgical outcomes
30 days after appendectomy
Study Arms (2)
Pregnant patients who underwent laparoscopic appendectomy
Pregnant patients who underwent laparoscopic appendectomy
Pregnant patients who underwent open appendectomy
Pregnant patients who underwent open appendectomy
Interventions
Appendectomy - laparoscopic or open
Eligibility Criteria
Study population consists of pregnant women who were pregnant during appendectomy confirmed either before or after the surgical procedure. The population was derived from the billing information from years 2010-2020 of the national health insurance fund of Estonia.
You may qualify if:
- Women with confirmed pregnancy who underwent appendectomy for acute appendicitis.
You may not qualify if:
- Women who were not pregnant when having an appendectomy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
North Estonia Medical Centre
Tallinn, Estonia
Related Publications (3)
Lee SH, Lee JY, Choi YY, Lee JG. Laparoscopic appendectomy versus open appendectomy for suspected appendicitis during pregnancy: a systematic review and updated meta-analysis. BMC Surg. 2019 Apr 25;19(1):41. doi: 10.1186/s12893-019-0505-9.
PMID: 31023289BACKGROUNDProdromidou A, Machairas N, Kostakis ID, Molmenti E, Spartalis E, Kakkos A, Lainas GT, Sotiropoulos GC. Outcomes after open and laparoscopic appendectomy during pregnancy: A meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2018 Jun;225:40-50. doi: 10.1016/j.ejogrb.2018.04.010. Epub 2018 Apr 9.
PMID: 29656140BACKGROUNDZeng Q, Aierken A, Gu SS, Yao G, Apaer S, Anweier N, Wu J, Zhao JM, Li T, Tuxun T. Laparoscopic Versus Open Appendectomy for Appendicitis in Pregnancy: Systematic Review and Meta-Analysis. Surg Laparosc Endosc Percutan Tech. 2021 May 3;31(5):637-644. doi: 10.1097/SLE.0000000000000943.
PMID: 33935257BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator, general surgeon, MD
Study Record Dates
First Submitted
June 12, 2022
First Posted
June 24, 2022
Study Start
November 1, 2021
Primary Completion
June 1, 2022
Study Completion
June 1, 2022
Last Updated
June 24, 2022
Record last verified: 2022-06