Prediction of Knee Injuries Through System Dynamics Modeling

NCT05430581 | Unknown

• 1 other identifier: 12756
• Study Type: observational
• Target: 99
• Locations: 1 country
• Sites: 1

Brief Summary

The large number of studies in the recent decade dealing with knee injury prevention seems not effective enough to cause a decline in knee injury rates. Thus, it has been proposed to use non-linear mathematical models that simulate the operation of complex and dynamic systems. The present study aims to analyze the dynamic relationships of the risk factors for knee injuries through system dynamics modeling to effectively predict and prevent knee injury. The first part of this project includes a qualitative study informing the theoretical non-linear interrelationships among the risk factors. The aim is to examine the initial hypothetical model formulated in the first part of the project through statistical analysis such as factor analysis and structural equation modeling. Pre-season and in-season data from questionnaires and biomechanical measurements for risk factors will be collected from at least 100 athletes who participate in high-risk sports. The athletes will be monitored for injuries during one season, and these data will be used in the next part of the research plan. The next part of the project aims to develop a dynamic simulation model for predicting knee injuries using specific equations. The function of the simulation model will predict the propensity of knee injuries over time. The next step includes the validation and calibration of the model based on the knee injuries that occurred during the season. The validated and calibrated model will then provide implications for effective policy decisions in knee injury prevention.

Conditions

Sport Injury; Sports Physical Therapy

Outcome Measures

Primary Outcomes (11)

• Score in landing error scoring system test

  The landing technique of the athletes will be assessed using the test landing error scoring system. The LESS assesses the quality of movement during landing based on a 19-point continuous scale. A maximum score of 19 can be reached; the lower the score, the better the landing technique.

  Baseline test

• BMI (kg/m^2)

  Baseline test

• Leg length (cm)

  Baseline test

• Tibia length (cm)

  Baseline test

• Demographic, history of injury, and activity level

  Using questionnaires data will be collected regarding the age, level of competition, details of previous injuries, playing position, training volume

  Baseline test

• Passive range of motion with Goniometer

  It will be assessed the range of motion for the following movements: Hip external/internal rotation, knee hyperextension, and ankle dorsiflexion

  Baseline test

• Core muscle endurance

  It will be measured the time in seconds until exhaustion to maintain the position in the following tests: side bridge test, prone bridge test, extensor endurance test

  Baseline test

• Muscle strength

  Muscle strength examination with hand held dynamometer for the following muscles: quadriceps, hamstrings and hip abductors

  Baseline test

• Balance

  Assessment of the balance with the pressure platform during the task of single leg drop jump

  Baseline test

• Muscle activation

  Assessment of quadriceps and hamstrings muscle activation with surface electromyography in the single leg hop for distance

  Baseline test

• Incidence of knee injuries

  Collection data through questionnaire for knee injuries of the athletes during the season that cause at least one-day time loss from game or training

  1 year

Secondary Outcomes (1)

• Incidence of other lower extremity injuries

  1 year

Eligibility Criteria

• Age: 17 Years - 40 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

100 healthy athletes (17-40 years old) that participate in sports that include activities such as jumping, slowing down, and change of direction by pivoting such as football, basketball, and handball

You may qualify if:

• Healthy professional athletes that participate in team sports (football, handball, basketball)

You may not qualify if:

• Injured athletes

Sponsors & Collaborators

• University of Patras: lead

Study Sites (1)

University of Patras

Aigio, 25100, Greece

Location

Related Publications (3)

• Fonseca ST, Souza TR, Verhagen E, van Emmerik R, Bittencourt NFN, Mendonca LDM, Andrade AGP, Resende RA, Ocarino JM. Sports Injury Forecasting and Complexity: A Synergetic Approach. Sports Med. 2020 Oct;50(10):1757-1770. doi: 10.1007/s40279-020-01326-4.

  PMID: 32757162 BACKGROUND

• Bittencourt NFN, Meeuwisse WH, Mendonca LD, Nettel-Aguirre A, Ocarino JM, Fonseca ST. Complex systems approach for sports injuries: moving from risk factor identification to injury pattern recognition-narrative review and new concept. Br J Sports Med. 2016 Nov;50(21):1309-1314. doi: 10.1136/bjsports-2015-095850. Epub 2016 Jul 21.

  PMID: 27445362 BACKGROUND

• Hulme A, Thompson J, Nielsen RO, Read GJM, Salmon PM. Towards a complex systems approach in sports injury research: simulating running-related injury development with agent-based modelling. Br J Sports Med. 2019 May;53(9):560-569. doi: 10.1136/bjsports-2017-098871. Epub 2018 Jun 18.

  PMID: 29915127 BACKGROUND

Study Officials

• Sofia A. Xergia

  University of Patras

  STUDY DIRECTOR

• Elias Tsepis

  University of Patras

  STUDY DIRECTOR

• Konstantinos Fousekis

  University of Patras

  STUDY DIRECTOR

• Charis Tsarbou

  University of Patras

  PRINCIPAL INVESTIGATOR

• George Papageorgiou

  European University Cyprus

  STUDY DIRECTOR

• Nikolaos I. Liveris

  University of Patras

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 15, 2022
• First Posted: June 24, 2022
• Study Start: July 22, 2022
• Primary Completion: May 22, 2023
• Study Completion: December 31, 2024
• Last Updated: December 20, 2023

Record last verified: 2023-12

Locations

GR (1)