NCT05428839

Brief Summary

This study is an exploratory, multicenter study of up to 300 subjects diagnosed with obstructive sleep apnea who are being evaluated for airway surgery. Subjects will undergo standard evaluation for airway surgery as part of standard of care. In addition to the standard airway assessment, a simple, non-invasive measurement of the width of the inside of each subjects mouth will be performed. This measurement takes 2-3 minutes to perform.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2022

Typical duration for not_applicable

Geographic Reach
1 country

10 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 10, 2022

Completed
1 day until next milestone

Study Start

First participant enrolled

May 11, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

June 23, 2022

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 11, 2024

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2025

Completed
Last Updated

October 17, 2024

Status Verified

March 1, 2024

Enrollment Period

1.7 years

First QC Date

May 10, 2022

Last Update Submit

October 15, 2024

Conditions

Keywords

OSA

Outcome Measures

Primary Outcomes (1)

  • Measurement of pharyngeal width to determine if there is correlation between pharyngeal width and presence or absence of complete concentric collapse at the soft palate during drug induced sleep endoscopy

    Pharyngeal width will be measured in millimeters using a caliper

    Baseline, prior to routine diagnostic drug induced sleep endoscopy

Interventions

A simple, non-invasive measurement of the pharyngeal width inside each subjects mouth

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient meets the indications for the Inspire Upper Airway Stimulation
  • Patient is being evaluated by drug-induced sleep endoscopy as standard-of-care diagnostic for OSA surgery.

You may not qualify if:

  • Patient is unable to lie supine for 2-3 minutes in order to undergo airway measurement
  • Any other reason the investigator deems that the patient is unfit for participation in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (10)

Valley ENT

Scottsdale, Arizona, 85260, United States

RECRUITING

Rush University Medical Center

Chicago, Illinois, 60612, United States

RECRUITING

Mason City Clinic

Mason City, Iowa, 50401, United States

RECRUITING

Massachusetts Eye and Ear Infirmary

Boston, Massachusetts, 02114, United States

RECRUITING

ENT Specialty Care of MN

Saint Louis Park, Minnesota, 55404, United States

RECRUITING

Ohio State University

Columbus, Ohio, 43121, United States

RECRUITING

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

RECRUITING

Thomas Jefferson University

Philadelphia, Pennsylvania, 19107, United States

RECRUITING

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15219, United States

RECRUITING

Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

RECRUITING

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 10, 2022

First Posted

June 23, 2022

Study Start

May 11, 2022

Primary Completion

January 11, 2024

Study Completion

January 31, 2025

Last Updated

October 17, 2024

Record last verified: 2024-03

Data Sharing

IPD Sharing
Will not share

Locations