Serial Casting for Upper Extremity Burn Contractures

NCT05425433 | Completed

• 1 other identifier: 22.084
• Study Type: interventional
• Target: 12
• Locations: 1 country
• Sites: 1

Brief Summary

The use of a splint, serial casting and passive stretching have been described in the literature as conservative interventions to manage joint contractures after burn injury. There is a paucity of literature investigating the effect of serial casting on scar contractures following upper extremity (UE) burn injury in adults and a lack of studies using strong methodological approaches. There are also no studies investigating the effect of casting on hypertrophic scars (HSc) and on self-reported UE function. This study is a longitudinal case series design with a criteria for change on the use of serial casting for the treatment of upper extremity burn contractures. The purpose of this study is to estimate the extent to which range of motion (AROM and PROM), scar characteristics and patient-reported upper-extremity function changes following an individually-tailored serial casting treatment program after switching from one week of usual care and to determine if these changes can be maintained 3 weeks after stopping serial casting, for adult burn survivors who developed an upper-extremity joint contracture greater than 15% normal range of motion within 1-year post-burn. This study will be a longitudinal case series design with a criteria for change. A minimum of 12 participants will be recruited from the "Centre d'expertise pour les victimes de brûlures graves de l'ouest du Québec" (CEVBGOQ) and will undergo one week of "usual care". If the PROM of the joint does not improve after one week of usual care, the participant will start the serial casting process, which will be prescribed by the treating OT. PROM/AROM and scar characteristics will be measured using a revised goniometry protocol that incorporates cutaneokinematics (CKM) principles and precise skin measures (DermaScan C, Cutometer®, Mexameter® and Tewameter®) at baseline, every Monday and Friday of the treatment weeks and 3 weeks after treatment cessation. Self-reported UE function and satisfaction related to scarring will be assessed at baseline and 3 weeks after treatment cessation using the QuickDASH and the patient satisfaction assessment scale (PSAS). Analysis on ROM and scar characteristic will be conducted using a graphical representation with a projected "usual care" regression line to count how many outcomes were over the line once the treatment was introduced. This study will contribute to building evidence for the use of serial casting following UE burn contractures in the adult population.

Conditions

Burn Contracture of Skin

Keywords

Burns, Burn Rehabilitation, Serial Casting

Outcome Measures

Primary Outcomes (2)

• Passive range of motion changes

  PROM measures by goniometer (standard and revised goniometry protocol)

  Baseline, Every Monday and Friday of Serial casting intervention weeks (tailored to the patient's needs), 3 weeks post intervention

• Active range of motion changes

  AROM measures by goniometer (standard and revised goniometry protocol)

  Baseline, Every Monday and Friday of Serial casting intervention weeks (tailored to the patient's needs), 3 weeks post intervention

Secondary Outcomes (7)

• Patient reported upper-extremity function changes

  Baseline, 3 weeks post intervention

• Scar patient satisfaction

  Baseline, 3 weeks post intervention

• Skin Thickness Changes

  Baseline, Every Monday and Friday of Serial casting intervention weeks (tailored to the patient's needs), 3 weeks post intervention

• Skin Elasticity Changes

  Baseline, Every Monday and Friday of Serial casting intervention weeks (tailored to the patient's needs), 3 weeks post intervention

• Skin Erythema Changes

  Baseline, Every Monday and Friday of Serial casting intervention weeks (tailored to the patient's needs), 3 weeks post intervention

Study Arms (1)

Serial casted joint

EXPERIMENTAL

Tailored serial casting intervention following 1 week of usual care

Other: Tailored serial casting intercention

Interventions

Tailored serial casting intercention OTHER

Every participant will undergo 1 week of usual care for the affected joint according to the OT's prescription (static progressive, dynamic or serial static) combined with stretching, moisturizers, pressure therapy, or thermal modalities. After the one week of splinting, if the PROM of the targeted joint does not improve, the participant will start serial casting (Monday to Friday). Patients will have a cast applied on Monday morning and worn for 24hrs/day or for 48hrs according to the OTs and treating physician's decision (rationale documented).The OT will decide how many weeks the participant will be wearing casts and the rationale to stop this treatment will be documented. When the treatment is stopped, patients will be encouraged to wear a maintenance splint for the following 2 weeks.

Serial casted joint

Eligibility Criteria

• Age: 16 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Burn survivors with \>15% loss of PROM of their PIP, MCP, wrist, or elbow in either: flexion, extension, ulnar deviation or radial deviation.
• Fire, flame or scald burn injury
• ≥16 years old
• have provided informed consent.

You may not qualify if:

• Frostbite, chemical or electrical burn injury
• A premorbid musculoskeletal or neurological disorder that limited their ROM
• Have sustained a neurological injury secondary to the burn injury
• A psychiatric or cognitive disorder that limits their ability to follow the research protocol
• Have been diagnosed with heterotopic ossification
• PROM is contraindicated for any reason
• Do not understand English or French.

Sponsors & Collaborators

• Centre hospitalier de l'Université de Montréal (CHUM): lead

Study Sites (1)

Hôpital de réadaptation Villa Médica

Montreal, Quebec, H2X 1C9, Canada

Location

MeSH Terms

Conditions

Burns

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

• Bernadette Nedelec, PhD

  CRCHUM

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 14, 2022
• First Posted: June 21, 2022
• Study Start: September 20, 2022
• Primary Completion: August 31, 2025
• Study Completion: September 20, 2025
• Last Updated: March 20, 2026

Record last verified: 2026-03

Locations

CA (1)