Application of Standardized Green Channel Treatment System for Ischemic Stroke in Xi 'an

NCT05424978 | Recruiting

• 1 other identifier: SYLL-2021-024
• Study Type: observational
• Target: 3,600
• Locations: 1 country
• Sites: 1

Brief Summary

Objective: To observe the practical application of the standardized green channel treatment system for stroke in Xi 'an in the real world. Methods: Clinical data and information of patients with acute ischemic stroke who received standardized green channel treatment for stroke were collected, and a multicenter observational clinical study was carried out in the real world to evaluate the prognosis, mortality, incidence of asymptomatic and symptomatic cerebral hemorrhage, incidence of pneumonia, and recurrence rate of stroke after 90 days.

Conditions

Acute Ischemic Stroke; Thrombolysis; Endovascular Treatment

Outcome Measures

Primary Outcomes (1)

• Rate of function independent

  Rate of modified Rankin Scale(mRS) score less than 3 at 90 days

  90 days after onset

Secondary Outcomes (3)

• Rate of mortality

  90 days after onset

• Rate of stroke recurrence

  90 days after onset

• Rate of cerebral hemorrhage and pneumonia

  During hospitalization.

Interventions

Standardized green channel treatment methods for stroke OTHER

The measures include six measures: timely triage by triage desk nurses; Rapid evaluation by emergency room physician; If stroke is suspected, the green channel for nosocomial stroke should be activated immediately. Stroke greenway doctors and stroke nurses accompanied patients to complete CT examination; Intravenous thrombolysis in emergency rooms or CT rooms; Suspected macrovascular disease, if the onset time is less than 6 hours, quickly go to the catheter room for intravascular treatment; If the onset time was more than 6 hours, multi-mode imaging was used to quickly evaluate the ischemic penumbra and vascular occlusion, and then the patients were sent to the catheter room for intravascular treatment as soon as possible.

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with acute ischemic stroke within 24 hours of onset; Receive standardized green channel treatment for stroke

You may qualify if:

• years old;
• Consistent with the diagnosis of acute ischemic stroke;
• hours from onset to enrollment;
• Informed consent

You may not qualify if:

• Patients who refuse to receive intravenous thrombolysis or intravascular intervention (including intravascular mechanical thrombolysis and arterial thrombolysis);
• Stroke patients caused by brain tumor, brain trauma and blood diseases;
• Those with a history of stroke and sequelae affecting the outcome assessment, namely, mRS 2 points before the onset of this stroke;
• Combined with claudication osteoarthritis rheumatoid arthritis gout arthritis and other limb dysfunction and affect the neurological function examination;
• Patients with severe hepatic and renal insufficiency (Note: Hepatic insufficiency refers to ALT or AST values greater than 2 times the upper normal limit; Renal insufficiency refers to blood creatinine value greater than 2 times the normal upper limit);
• Suffering from other serious life-threatening diseases with an expected survival time of less than 3 months;
• Other diseases that limit neurological function evaluation or affect patient follow-up;
• A woman planning to be pregnant or breastfeeding;
• Currently participating in other clinical trials;
• Refuse to participate in the registration of investigators

Sponsors & Collaborators

• Xi'an No.3 Hospital: lead

Study Sites (1)

Xi 'an No.3 Hospital

Xi'an, Shaanxi, 710018, China

RECRUITING

MeSH Terms

Conditions

Ischemic Stroke

Condition Hierarchy (Ancestors)

Stroke; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Ye Tian, Doctor

  The dean

  STUDY DIRECTOR

Central Study Contacts

Mingze Chang, Doctor

CONTACT

8615609250698; changmingze191@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 90 Days
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 1, 2022
• First Posted: June 21, 2022
• Study Start: June 1, 2022
• Primary Completion: July 31, 2025
• Study Completion (Estimated): July 31, 2028
• Last Updated: January 26, 2024

Record last verified: 2024-01

Locations

CN (1)