Intermediate Visual Space Perception

NCT05419713 | Recruiting

• 2 other identifiers: 94.0302R01EY033190
• Study Type: interventional
• Target: 180
• Locations: 1 country
• Sites: 1

Brief Summary

The ability to judge the locations of various objects from oneself during self-motion in the intermediate distance range (\~2-25m) is crucial for successful performance of activities of daily living, such as walking and driving. However, little is known about the mechanisms of visual space perception involved in judging distance, the focus of this project, in the planning and/or execution of self-motion in the natural 3D environment. The theoretical knowledge to be gained from this project will contribute to the scientific literature and provide insights into how eye and neurological defects could impair visual space perception, wayfinding, and mobility.

Conditions

Vision

Outcome Measures

Primary Outcomes (2)

• Visual mechanisms of intermediate distance space perception (distance) before and after self-motion

  Subjects will judge perceived distances (cm) of test targets from themselves before self-motion to establish a baseline measure. Subjects will then undergo self-motion for an average of 10 sec, and stop at a predetermined location. Then subjects will again judge the perceived distance (cm) of test targets after the self-motion. The change in perceived distance (cm) from baseline will reveal if their perception is affected by environmental factors, internal perceptual process and/or cognitive process.

  During procedure, an average of 10 sec.

• Visual mechanisms of intermediate distance space perception (height) before and after self-motion.

  Subjects will judge perceived heights (cm) of test targets relative to the floor or ceiling before self-motion to establish a baseline measure. Subjects will then undergo self-motion for an average of 10 sec, and stop at a predetermined location. Then subjects will again judge the perceived height (cm) of test targets after the self-motion. The change in perceived height (cm) from baseline will reveal if their perception is affected by environmental factors, internal perceptual process and/or cognitive process.

  Druing procedure, an average of 10 sec.

Study Arms (1)

Visual scences

EXPERIMENTAL

Lit target locations in visual environment will be varied and subjects' perceived locations will be measured.

Other: Visual Stimuli for Space Perception

Interventions

Visual Stimuli for Space Perception OTHER

The visual environment (e.g., target locations and texture backgrounds) will be varied and human behavioral responses (judged distances) will be measured to reveal the space perception and cognitive processes underlying space perception and navigation.

Visual scences

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Adults (up to 40 years of age)
• Children (18 years and older)
• Normal, or corrected-to-normal, visual acuity (at least 20/20)
• Stereo acuity (\<20 arc sec).

You may not qualify if:

• Self-reported history of visual and eye diseases
• Physical movement restrictions.
• Vulnerable populations such as pregnant women will be excluded owing to the extensive time commitment required of the subjects.

Sponsors & Collaborators

• University of Louisville: lead
• National Eye Institute (NEI): collaborator

Study Sites (1)

University of Louisville

Louisville, Kentucky, 49292, United States

RECRUITING

Study Officials

• Zijiang He

  University of Louisville

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Zijiang He, Ph.D.

CONTACT

502-852-6779; zjhe@louisville.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: June 1, 2022
• First Posted: June 15, 2022
• Study Start: September 30, 2021
• Primary Completion: June 30, 2025
• Study Completion: June 30, 2025
• Last Updated: September 25, 2024

Record last verified: 2024-09

Locations

US (1)