NCT05418699

Brief Summary

To evaluate, in real life, the effect of closed-loop devices on the improvement of glycemic control in diabetic patients managed in the endocrinology departments of secondary care hospitals.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
410

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2022

Typical duration for all trials

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 10, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 14, 2022

Completed
3 months until next milestone

Study Start

First participant enrolled

September 26, 2022

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 10, 2023

Completed
1.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2025

Completed
12 months until next milestone

Results Posted

Study results publicly available

March 12, 2026

Completed
Last Updated

March 12, 2026

Status Verified

February 1, 2026

Enrollment Period

1 year

First QC Date

June 10, 2022

Results QC Date

February 20, 2026

Last Update Submit

February 20, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • HbA1c Level

    Hemoglobin A1c is an indicator of your long-term glucose levels. Normal range for the hemoglobin A1c level is between 4% and 5.6%

    At 3 months

Secondary Outcomes (19)

  • HbA1c Level

    At 6 months

  • HbA1c Level

    At 12 months

  • Time in Range

    At 3 months

  • Time in Range

    At 6 months

  • Time in Range

    At 12 months

  • +14 more secondary outcomes

Study Arms (1)

Type I diabetic patient

Device: closed-loop insulin pump

Interventions

Follow up of patients with real-time closed-loop insulin delivery systems

Type I diabetic patient

Eligibility Criteria

Age7 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Type I diabetic patients with a closed-loop insulin pump between April 2020 and August 2023

You may qualify if:

  • type I diabetic
  • with a closed-loop insulin pump

You may not qualify if:

  • under legal protection order
  • patient or legal guardian objecting to the use of the data in the research

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

CH Béthune-Beuvry

Béthune, France

Location

CH Boulogne-sur-Mer

Boulogne-sur-Mer, France

Location

CH Dax

Dax, France

Location

CHI Mont de Marsan et du Pays des Sources

Mont-de-Marsan, France

Location

CH Périgueux

Périgueux, France

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Results Point of Contact

Title
Dr. Didier Gouet
Organization
Groupe Hospitalier de la Rochelle Ré Aunis

Study Officials

  • Didier GOUET, MD

    Groupe Hospitalier de la Rochelle Ré Aunis

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 10, 2022

First Posted

June 14, 2022

Study Start

September 26, 2022

Primary Completion

October 10, 2023

Study Completion

March 31, 2025

Last Updated

March 12, 2026

Results First Posted

March 12, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will share

The database will be made available on a general-purpose open repository. Medical Subject Headings (MESH) terms will be used to describe clinical data. International standard unit will be used. Keyword are type I diabetes, Insulin Infusion Systems, Patient Outcome Assessment

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Data will be made available with publication. A Digital Object Identifier will be used.
Access Criteria
The only available version will be the locked database. With the exception of dates, all data will be made available. Dates will only be collected to verify the quality of the clinical trial execution. They do not add to the clinical question, and may be a means of indirectly identifying patients.

Locations