NCT05418504

Brief Summary

Dental anesthesia is considered by far one of the main procedures in dentistry; the performance of a good dental anesthesia with a correct technique is paramount in controlling pain, facilitating the work of the dentist and gaining the confidence and cooperation of the patient Tramadol is an FDA-approved medication for pain relief indicated mainly for moderate to severe pain, it is an opioid with 6 hours Half-Life and different dosages as 50mg, 100mg, 200mg and 300mg. Due to possible abuse and addiction potential, limitations to its use should be for pain that is refractive to other pain medication, such as non-opioid pain medication, unfortunately, the almost non-existent of censorship in Algeria and the disorderly framing made the obtain of tramadol as a medicine very easy which has led to a very alarming abuse of this drug

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
400

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started May 2022

Shorter than P25 for phase_4

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2022

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

June 10, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 14, 2022

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2022

Completed
Last Updated

June 16, 2022

Status Verified

June 1, 2022

Enrollment Period

3 months

First QC Date

June 10, 2022

Last Update Submit

June 14, 2022

Conditions

Keywords

Dental anesthesiatramadol

Outcome Measures

Primary Outcomes (1)

  • Anesthesia dose

    Anesthesia carbols number through which both conc and dose needed in dental intervention in both arms

    3 months

Study Arms (2)

Non- Tramadol

ACTIVE COMPARATOR

the control group represented by dental patients who are not a tramadol addict

Drug: Dental anesthesia

Tramadol

ACTIVE COMPARATOR

The study group with patients seeking dental service but also are tramadol addict.

Drug: Dental anesthesia

Interventions

Dental anesthesia, used to do any dental procedure

Non- TramadolTramadol

Eligibility Criteria

Age18 Years - 65 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Males
  • ≥18 years
  • With no comorbid conditions (HTN, Diabetes \& Epilepsy)
  • Tramadol addict (regular tramadol user)

You may not qualify if:

  • Females
  • ˂ 18 years
  • With comorbid conditions (HTN, Diabetes \& Epilepsy)
  • ≥ 65 years males

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Doaa El-Bohy

Cairo, 11817, Egypt

RECRUITING

Future University in egypt

Cairo, Egypt

RECRUITING

MeSH Terms

Interventions

Anesthesia, Dental

Intervention Hierarchy (Ancestors)

AnesthesiaAnesthesia and AnalgesiaDentistry

Study Officials

  • Doaa MS El-Bohy, PhD

    FUE

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Doaa MS El-Bohy, PhD

CONTACT

Heba A ElRamly, PhD

CONTACT

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
SCREENING
Intervention Model
PARALLEL
Model Details: The recruited participants will then be divided into 2 groups the control group represented by dental patients who are not a tramadol addict \& The study group with patients seeking dental service but also are tramadol addict.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assisstant professor

Study Record Dates

First Submitted

June 10, 2022

First Posted

June 14, 2022

Study Start

May 1, 2022

Primary Completion

August 1, 2022

Study Completion

August 1, 2022

Last Updated

June 16, 2022

Record last verified: 2022-06

Locations