Oral Health and Vitamin D in Stroke Patients

NCT05418335 | Completed

• 1 other identifier: AIBU-FTR-EY-06
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

Stroke is a common, serious and restrictive global health problem. Restricting the activities of daily living of stroke patients impairs patients' ability to pay attention to oral hygiene. Facial paresis and tongue weakness due to stroke may cause a decrease in the control of dental prostheses and the removal of food residues in the oral cavity. Food residues and saliva contaminated with bacteria as a result of poor oral hygiene can result in pneumonia when aspirated due to oropharyngeal dysphagia. In the literature, it has been shown that there are significant relationships between periodontal health and vitamin D and calcium intake, and that dietary supplementation with calcium and vitamin D can improve periodontal health, increase bone mineral density in the mandible, and inhibit alveolar bone resorption. In line with all these data, our hypothesis in this study is to investigate the relationship between oral health and vitamin D levels in stroke patients in rehabilitation units.

Conditions

Stroke; Oral Disease; D Vitamin Deficiency

Outcome Measures

Primary Outcomes (4)

• Barthel Index

  It is a simple, understandable index that includes all the parameters of daily living activities. It consists of 10 sub-headings: eating, bathing, self-care, dressing, bladder control, bowel control, toilet use, chair/bed transfer, mobility, and use of stairs. Its scoring ranges from 0-100.

  Baseline

• Oral Health Impact Profile -14

  Oral health-related quality of life is the individual's personal perception of how oral health affects their quality of life and general health. Oral health impact profile is a scale system that evaluates this perception with two questions on functional limitation, physical pain, psychological discomfort, physical, psychological and social disability and handicap. It is concluded that as the total score increases, the severity of the problem increases and the quality of life decreases. It is a scale that evaluates oral health-related quality of life with a questionnaire consisting of a total of 14 questions and 7 sub-headings (functional limitation, physical pain, psychological discomfort, physical, psychological and social disability and disability). Each item is scored as 0 (never), 1 (hardly ever), 2 (occasionally), 3 (fairly often), 4 (very often). High score indicates reduced quality of life15.

  Baseline

• DMFT Index (Decayed-Missing-Filled-Teeth )

  It shows the number of decayed teeth, filled teeth and teeth extracted due to caries per capita

  Baseline

• Periodontal Disease Index

  The mesial, distal, facial and lingual areas of each of the teeth are evaluated.

  Baseline

Secondary Outcomes (3)

• Beck Depression Inventory

  Baseline

• Plaque Index

  Baseline

• Gingival Index

  Baseline

Study Arms (2)

stroke group

stroke history at least 3 months ago

Other: Clinical examination, functional status evaluation

Control group

Healthy control

Other: Clinical examination, functional status evaluation

Interventions

Clinical examination, functional status evaluation OTHER

Barthel Index, Oral Health Impact Profile 14, Beck Depression Inventory, Stroke Impact Scale 3, Plaque Index, Calculus Index, Periodontal Disease Index, Simplified Oral Hygiene Index assesment, DMFT Index

Control group; stroke group

Eligibility Criteria

• Age: 50 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Stroke patients and healthy control group will be included in the study.

You may qualify if:

• Having a history of ischemic stroke at least 3 months
• Age between 50-75

You may not qualify if:

• The patient has moderate to severe dementia or mental retardation, which may cause limitations in examination, testing and treatment.

Sponsors & Collaborators

• Abant Izzet Baysal University: lead

Study Sites (1)

Elif Yakşi

Merkez, Bolu, 14030, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Stroke; Mouth Diseases; Vitamin D Deficiency

Interventions

Restraint, Physical

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Stomatognathic Diseases; Avitaminosis; Deficiency Diseases; Malnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Behavior Control; Therapeutics; Immobilization; Investigative Techniques

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Doctor

Study Record Dates

• First Submitted: June 10, 2022
• First Posted: June 14, 2022
• Study Start: July 12, 2022
• Primary Completion: July 15, 2022
• Study Completion: October 1, 2022
• Last Updated: October 12, 2022

Record last verified: 2022-06

Locations

TU (1)