NCT05410613

Brief Summary

The purpose of this study will investigate the effects of combined electromagnetic field and a plantar resistance exercise therapy versus electromagnetic field on healing of venous leg ulcer .

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 20, 2022

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

March 14, 2022

Completed
3 months until next milestone

First Posted

Study publicly available on registry

June 8, 2022

Completed
7 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2022

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 20, 2022

Completed
Last Updated

June 8, 2022

Status Verified

June 1, 2022

Enrollment Period

5 months

First QC Date

March 14, 2022

Last Update Submit

June 5, 2022

Conditions

Outcome Measures

Primary Outcomes (3)

  • Ulcer surface area

    Ulcer surface (UAS) would be calculated by placing a piece of sterilized transparency film over the ulcer and tracing the ulcer perimeter on the film with fine tipped transparency marker.

    two months

  • Ulcer volume measurement

    Ulcer volume : The ulcer would be traced on transparent paper and placed over the metric graph paper to have the longest length and width. * A disposable measuring tape would be directed into the deepest point of the ulcer to record the ulcer depth. * (Width x length x depth) would be calculated to have the volume of the ulcer

    two months

  • Pressure Ulcer Scale for Healing (PUSH)

    Categorize the ulcer with respect to surface area, exudate, and type of wound tissue

    two months

Study Arms (3)

combined electromagnetic field and a plantar resistance

EXPERIMENTAL
Combination Product: electromagnetic field and a plantar resistance exercise

electromagnetic field

EXPERIMENTAL
Device: Pulsed electromagnetic field

conservative treatment for the ulcer

ACTIVE COMPARATOR
Other: usual care

Interventions

Pulsed electromagnetic field therapy applied with intensity equal to 3mt and frequency of magnetic field impulses equal to 4 Hz. a plantar resistance exercise therapy by the StepIt rocker pedal, the overall exercise program will be to exercise on the pedal with the index leg for 1 min - then rest it for 1min - and to repeat this 10 times (20 minutes). This regime will be done twice daily (e.g .morning and evening).

combined electromagnetic field and a plantar resistance

Pulsed electromagnetic field therapy applied with intensity equal to 3mt and frequency of magnetic field impulses equal to 4 Hz

electromagnetic field

standard general advice according to hospital protocol

conservative treatment for the ulcer

Eligibility Criteria

Age40 Years - 55 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • patients with venous leg ulcer

You may not qualify if:

  • patients who have one or more of the following conditions:
  • peripheral vascular disease (PVD), (ABPI\<0.8).
  • venous leg ulcers with cellulitis or infection symptoms, as well as venous leg ulcers with necrotic tissue or slough or had more than one ulcer.
  • other types of ulcers, such as rheumatoid vasculitis, diabetic foot, and malignant ulceration; corticosteroids use ; patients with dementia or who were disoriented;
  • undertaken another physical therapy modality for ulcer healing.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Surgical department-Mansoura Health Insurance Hospital

Al Mansurah, Egypt

RECRUITING

MeSH Terms

Conditions

Varicose Ulcer

Interventions

Electromagnetic Fields

Condition Hierarchy (Ancestors)

Varicose VeinsVascular DiseasesCardiovascular DiseasesLeg UlcerSkin UlcerSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Electromagnetic PhenomenaMagnetic PhenomenaPhysical PhenomenaMagnetic Fields

Study Officials

  • ASMAA FAWZY EL-SAYED, lecturer

    Surgical department-Mansoura Health Insurance Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

ASMAA FAWZY EL-SAYED, lecturer

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
associate professor

Study Record Dates

First Submitted

March 14, 2022

First Posted

June 8, 2022

Study Start

January 20, 2022

Primary Completion

June 15, 2022

Study Completion

June 20, 2022

Last Updated

June 8, 2022

Record last verified: 2022-06

Locations