The Effect of Cognitive Reserve on Outcome After Stroke or Traumatic Brain Injury

NCT05407948 | Completed DMC

• 1 other identifier: NESandvikenstudy
• Study Type: observational
• Target: 87
• Locations: 1 country
• Sites: 1

Brief Summary

A long-term follow-up study of patients who acquired a stroke or traumatic brain injury (TBI) 5-15 years ago. Primary objective is to describe the interaction between measures of cognitive reserve and neuropsychological variables, psychological variables and healthcare usage in relation to outcome (i.e work return, satisfaction with life, psychological well-being and overall outcome) after stroke or traumatic brain injury. Secondary objectives are to describe differences in fatigue related to cognitive reserve after stroke or TBI and to describe differences in health-care usage related to cognitive reserve after stroke or TBI.

Conditions

Traumatic Brain Injury; Stroke

Keywords

Neuropsychology; Cognitive reserve; Return-to-work

Outcome Measures

Primary Outcomes (2)

• Return to work

  Degree of return to work according to degree of health insurance benefit received by the Swedish Social Insurance Agency

  5-15 years after injury

• Life Satisfaction Scale (LiSat-11)

  Life Satisfaction with life overall as well as with specific areas of life. Each area is grade on a scale from 1 to 6 where higher score indicates better satisfaction.

  5-15 years after injury

Secondary Outcomes (4)

• Glasgow Outcome Scale Extended (GOSE)

  5-15 years after injury

• Hospital Anxiety and Depression Scale (HADS)

  5-15 years after injury

• Fatigue

  5-15 years after injury

• Health care consumption

  3 years before injury to 4 years after injury

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Former patients at the Brain Injury Rehabilitation Team in Sandviken, Sweden, who had suffered a stroke or a traumatic brain injury between the years 2003-2016 were invited to participate in the study.

You may qualify if:

• Stroke or TBI between the years 2003-2016
• Previous or ongoing contact with the outpatient brain injury rehabilitation team in Region Gävleborg
• Currently living in Region Gävleborg. -

You may not qualify if:

• Patients with an intellectual disability (IQ\>70) or who have acquired a new brain injury will be excluded -

Sponsors & Collaborators

• Natascha Ekdahl: lead
• Karolinska Institutet: collaborator

Study Sites (1)

Sandvikens närsjukhus

Sandviken, Gävleborg County, 81189, Sweden

Location

Related Publications (36)

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MeSH Terms

Conditions

Brain Injuries, Traumatic; Stroke

Condition Hierarchy (Ancestors)

Brain Injuries; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Craniocerebral Trauma; Trauma, Nervous System; Wounds and Injuries; Cerebrovascular Disorders; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: June 1, 2022
• First Posted: June 7, 2022
• Study Start: November 2, 2018
• Primary Completion: March 30, 2022
• Study Completion: April 21, 2022
• Last Updated: June 7, 2022

Record last verified: 2022-06

Data Sharing

• IPD Sharing: Will not share

Locations

SE (1)