Postoperative Cognitive Dysfunction in Heart Surgery

NCT05406843 | Completed

• 1 other identifier: Observational
• Study Type: observational
• Target: 140
• Locations: 1 country
• Sites: 1

Brief Summary

To determine the rate of Postoperative Cognitive Dysfunction (POCD) in the early and late postoperative periods by comparing the preop and postop period mini mental status tests in participants undergoing open heart surgery, and to compare the results of the investgators clinic with the world literature.

Conditions

Postoperative Cognitive Dysfunction

Keywords

COGNITIVE DYSFUNCTİON; HEART SURGERY; POSTOPERATIVE DELIRIUM

Outcome Measures

Primary Outcomes (1)

• Evaluation of postoperative cognitive functions in participants undergoing open heart surgery.

  The aim is to understand whether there is a loss of cognitive functions in the postoperative period, according to the preoperative periods, by testing the participants with open heart surgery on the 3rd day, 7th day, and 2nd month after the surgery.

  1 year

Secondary Outcomes (1)

• Comparison with the literature.

  1 year

Study Arms (2)

Preoperative cognitive status of participants undergoing open heart surgery

Detection of postoperative cognitive impairment is difficult and it starts with testing in the preoperative period. In this study, it was aimed to determine postoperative cognitive impairment by comparing cognitive functions by using Minimental status test in the preoperative period in participants scheduled for open heart surgery for one year. It was planned to compare the obtained data in terms of participants undergoing valve and coronary bypass surgery, age, gender, diabetes, kidney disease, chronic obstructive pulmonary disease (COPD), surgical characteristics, bypass time, and crossclamping time.

Other: Preoperative cognitive functions of participants undergoing open heart surgery

Postoperative cognitive status of participants undergoing open heart surgery

Detection of postoperative cognitive impairment is difficult and it starts with testing in the preoperative period. In this study, it was aimed to determine the postoperative cognitive impairment by comparing it with the cognitive functions in the preoperative period using the Minimental status test in the postoperative period in participants scheduled for open heart surgery for a year. It was planned to compare the obtained data in terms of participants undergoing valve and coronary bypass surgery, age, gender, diabetes, kidney disease, chronic obstructive pulmonary disease (COPD), surgical characteristics, bypass time, and crossclamping time.

Other: Postoperative cognitive functions of particiants undergoing open heart surgery

Interventions

Preoperative cognitive functions of participants undergoing open heart surgery OTHER

Surgery times and cross-clamping times of the participants who will undergo open heart surgery were recorded.

Preoperative cognitive status of participants undergoing open heart surgery

Postoperative cognitive functions of particiants undergoing open heart surgery OTHER

Changes in mini mental test scores were recorded in the postoperative period.

Postoperative cognitive status of participants undergoing open heart surgery

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

A study was planned on 140 patients undergoing open heart surgery.

You may qualify if:

• age
• American Society of Anesthesiologists (ASA) II-III

You may not qualify if:

• \>75 age
• \<18 age
• Patients who died within 48 hours after the operation

Sponsors & Collaborators

• Kocaeli University: lead

Study Sites (1)

Kocaeli Üniversitesi Tıp Fakültesi Hastanesi

Kocaeli, İzmit, 41100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Postoperative Cognitive Complications; Cognition Disorders; Emergence Delirium

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Cognitive Dysfunction; Neurocognitive Disorders; Mental Disorders; Delirium; Confusion; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms

Study Officials

• Tülay Çardaközü

  Kocaeli University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant

Study Record Dates

• First Submitted: February 18, 2021
• First Posted: June 7, 2022
• Study Start: January 1, 2020
• Primary Completion: January 1, 2021
• Study Completion: August 1, 2021
• Last Updated: June 9, 2022

Record last verified: 2022-06

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
• Time Frame: starting 6 months after publication
• Access Criteria: The study results can be accessed by anyone who is a healthcare worker.

Locations

TU (1)