Triage - Symptoms and Other Predictors in an All-comer Emergency Department Population
EMERGE VI-VII
1 other identifier
observational
6,467
1 country
1
Brief Summary
This study is to evaluate a tool capable of improved risk prediction regarding the 30-day mortality. The primary objective of this study is hospitalization, ICU-admission, morbidity and mortality in correlation with external validation of International Early Warning Score (IEWS) and decision-making processes regarding diagnosis, treatment and disposition in the ED.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2022
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 17, 2022
CompletedFirst Submitted
Initial submission to the registry
May 24, 2022
CompletedFirst Posted
Study publicly available on registry
June 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 27, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2026
January 26, 2026
January 1, 2026
4 years
May 24, 2022
January 22, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
30-day mortality
30-day mortality is defined as death within 30 days of the day of presentation to the ED
within 30 days of the day of presentation to the ED
Secondary Outcomes (6)
Number of hospitalizations
at baseline (= day of presentation to the ED)
Number of ICU-admissions
at baseline (= day of presentation to the ED)
Death rate (In-hospital mortality)
from day of presentation to the ED to day of hospital discharge (assessed within 365 days of the day of presentation to the ED)
100-day mortality
within 100 days of the day of presentation to the ED
Number of institutionalisations
within 100 days of the day of presentation to the ED
- +1 more secondary outcomes
Study Arms (1)
patients admitted to emergency ward of the University Hospital Basel.
Interventions
heart rate, blood pressure, body temperature, respiration rate, peripheral capillary haemoglobin oxygen saturation)
Patients are asked how they assess their own mobility: - Stable walking without aids or limited mobility with aids (walking aid, wheelchair, lying down).
Assessment of level of consciousness by AVPUC scale (alert, new confusion, verbal, pain, unresponsive, new confusion)
Questionnaire with a predefined list of 37 symptoms
Patients over the age of 65 are asked the following: "generally asked: what matters most to you at the moment?" and "why is that important for you?".
Questionnaire consisting of 10 questions about the decision-making processes in the emergency department and the factors that form the basis of their decisions regarding the diagnosis, treatment, and disposition of the patient.
Mattling is a characteristic discoloration of the skin resulting from reduced skin blood flow and has been shown to be associated with tissue hypoperfusion. The MS provides a simple scale (0-5) to characterize the extent of skin mottling around the knee and the severity of mottling is associated with adverse outcomes.
The NRS is a segmented numeric version of the visual analog scale (VAS) in which a respondent selects a whole number (0-10 integers) that best reflects the intensity of his/her pain ('0' representing one pain extreme (e.g. "no pain") to '10' representing the other pain extreme (e.g. "pain as bad as you can imagine"))
The CFS is a commonly used score to assess frailty. It was developed within the Canadian Study of Health and Aging and consists of a 9-level ordinal scale ranging from very fit (score 1) to living with very severe frailty (score 8), and score 9 reserved for those who are terminally ill.
The PPI is derived from the photoplethysmography signal of pulse oximetry and represents the ratio between the pulsatile component (arterial compartment) and the non-pulsatile component (non-arterial tissues) of the light detected by the sensor. PPI can provide information for resuscitation in shock, outcome prediction in critically ill patients and may serve as an adjunct triage tool.
CRT provides a standardized assessment of capillary flow dynamics and is most assessed at the fingertip in clinical practice. A prolonged CRT in patients with septic, traumatic and cardiogenic shock has been associated with increased mortality and might be used as a resuscitation target in patients with septic shock.
Mental health complaints require safe, efficient risk stratification to distinguish primary psychiatric conditions from medical causes or comorbidities. Because current medical screening practices are inconsistent and unvalidated, this study will use prospective routine ED data to evaluate triage assessments of psychiatric likelihood and identify opportunities for standardized, evidence-based screening.
Delirium is a common and high-risk condition in older ED patients, and early detection is crucial to improve short- and long-term outcomes. This study will use routinely collected ED screening data (modified Confusion Assessment Method for the Emergency Department (mCAM-ED) and the four-item Abbreviated Mental Test (AMT-4)) to describe delirium prevalence and evaluate delirium identification in the emergency setting.
Eligibility Criteria
The study population will consist of all patients presenting to the ED of the University Hospital Basel and awaiting triage.
You may qualify if:
- Patients presenting to the ED of the University Hospital Basel over a timecourse of 9 weeks in 2022, 2024, 2026
You may not qualify if:
- Obstetric, ophthalmologic, and paediatric patients will not be included
- unwillingness to participate
- insufficient ability to communicate with the study personnel.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Emergency Medicine, University Hospital Basel
Basel, 4031, Switzerland
Related Publications (2)
Riedel HB, Espejo T, Dreher-Hummel T, Bingisser R, Nickel CH. Screening for elder mistreatment in a Swiss emergency department: a prospective cohort study. Swiss Med Wkly. 2024 Jun 10;154:3775. doi: 10.57187/s.3775.
PMID: 38875501DERIVEDAlbrecht R, Espejo T, Riedel HB, Nissen SK, Banerjee J, Conroy SP, Dreher-Hummel T, Brabrand M, Bingisser R, Nickel CH. Clinical Frailty Scale at presentation to the emergency department: interrater reliability and use of algorithm-assisted assessment. Eur Geriatr Med. 2024 Feb;15(1):105-113. doi: 10.1007/s41999-023-00890-y. Epub 2023 Nov 16.
PMID: 37971677DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Roland Bingisser, Prof. Dr. med.
University Hospital Basel, Department of Emergency Medicine
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 24, 2022
First Posted
June 1, 2022
Study Start
May 17, 2022
Primary Completion (Estimated)
May 27, 2026
Study Completion (Estimated)
December 31, 2026
Last Updated
January 26, 2026
Record last verified: 2026-01