Radiomics Combined With Frozen Section Prediction Model for Spread Through Air Space in Lung Adenocarcinoma
Preoperative CT-based Radiomics Combined With Intraoperative Frozen Section is Predictive of Spread Through Air Space in Early Lung Adenocarcinoma
1 other identifier
observational
900
0 countries
N/A
Brief Summary
a multifactorial model combining radiomics with frozen section analysis is a potential biomarker for assessing Spread Through Air Space during surgery, which can provide decision-making support to therapeutic planning for early-stage lung adenocarcinomas.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jul 2022
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 26, 2022
CompletedFirst Posted
Study publicly available on registry
June 1, 2022
CompletedStudy Start
First participant enrolled
July 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
May 12, 2023
CompletedJune 29, 2022
June 1, 2022
10 months
May 26, 2022
June 22, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Sensitivity
Testing the sensitivity of Radiomics to predict STAS using the area under receiver operating characteristic curve
24 hour before operation
Specificity
Testing the specificity of Radiomics to predict STAS using the area under receiver operating characteristic curve
24 hour before operation
Study Arms (3)
Training dataset
No interventions
External validation1
No interventions
External validation2
No interventions
Interventions
The high-throughput extraction of large amounts of quantitative image features from medical images
Eligibility Criteria
Patients with pulmonary nodules in the collaborating institutes.
You may qualify if:
- intraoperative frozen section diagnosis and final pathology diagnosis are available
- preoperative standard non-enhanced CT is available
- Pathologically confirmed
You may not qualify if:
- with a previous history of radiation therapy, chemotherapy or biopsy
- the time interval between the CT examination and surgery was more than two weeks
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 26, 2022
First Posted
June 1, 2022
Study Start
July 1, 2022
Primary Completion
May 1, 2023
Study Completion
May 12, 2023
Last Updated
June 29, 2022
Record last verified: 2022-06