NCT05399979

Brief Summary

This study aims to perform statistical inference and prediction of changes in fetal heart rate during active labor in healthy pregnant women by comparing three different machine learning methods

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,077

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 9, 2021

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 5, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 5, 2022

Completed
22 days until next milestone

First Submitted

Initial submission to the registry

May 27, 2022

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 1, 2022

Completed
Last Updated

June 3, 2022

Status Verified

June 1, 2022

Enrollment Period

11 months

First QC Date

May 27, 2022

Last Update Submit

June 1, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • fetal bradycardia

    fetal heart rate under 120 lpm for more than 10 minutes

    15 minutes

Interventions

Labor Neuraxial Analgesia

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

-Pregnant patients admitted to the labor and delivery unit of an academic center

You may qualify if:

  • Older than 18 years
  • Pregnancy requiring labor analgesia
  • Active labor
  • Request of neuraxial analgesia per patient and/or obstetrician
  • Received combined spinal-epidural technique

You may not qualify if:

  • Uterine tachysystole before neuraxial analgesia.
  • Baseline blood pressure \<90/60 mmHg.
  • Third trimester hemorrhage
  • Eclampsia
  • Allergies to local anesthetics or fentanyl.
  • Maternal fever.
  • Pruritus before performance of neuraxial analgesia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Augusta University Medical Center

Augusta, Georgia, 30907, United States

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 27, 2022

First Posted

June 1, 2022

Study Start

June 9, 2021

Primary Completion

May 5, 2022

Study Completion

May 5, 2022

Last Updated

June 3, 2022

Record last verified: 2022-06

Data Sharing

IPD Sharing
Will not share

Locations