Kinesiophobia in Familial Mediterranean Fever

NCT05398536 | Completed

• 1 other identifier: ssaka6
• Study Type: observational
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

Kinesiophobia is a common problem in patients with rheumatic disease and can cause physical inactivity, social isolation, disability, and poor quality of life. This study aimed to evaluate kinesiophobia and associated factors in patients with familial Mediterranean fever (FMF). All patients were evaluated in terms of sociodemographic characteristics and assessed using the Tampa Kinesiophobia Scale (TKS), International Physical Activity Questionnaire (IPAQ), Fatigue Severity Scale (FSS), and Hospital Anxiety and Depression Scale (HADS).

Conditions

FMF

Keywords

Kinesiophobia; fear-avoidance; physical activity; familial Mediterranean fever

Outcome Measures

Primary Outcomes (3)

• Tampa Kinesiophobia Scale (TKS)

  The TKS consists of 17 items scored on a 4-point Likert scale and measures fear of movement/(re)injury. The questions include the parameters of injury/reinjury and fear-avoidance in work-related activities \[15\]. The total score is obtained by summing all items, and a higher score indicates greater fear of movement. A total score greater than 37 is regarded as indicating a high level of kinesiophobia

  at the enrollment

• Hospital Anxiety and Depression Scale (HADS)

  The scale consists of 14 items divided into the depression and anxiety subscales, each with 7 items. The items on the scale are scored from 0 to 3 using a 4-point Likert scale. The scores of the odd-numbered items are summed to obtain the anxiety subscale (HADS-A) score and the even-numbered items are summed to obtain the depression subscale (HADS-D) score. Possible scores for each subscale range from 0 to 21.

  at the enrollment

• International Physical Activity Questionnaire (IPAQ)

  In the IPAQ, respondents estimate how often and for how long they engaged in various activities in the last 7 days. To determine PA levels, the known metabolic equivalent (MET) for each activity is multiplied by its duration and frequency to obtain a score in MET minutes. MET values used in this study were 8.0 for vigorous physical activity (VPA) \[8, 19\], 4.0 for moderate physical activity (MPA), and 3.3 for light physical activity (LPA). The overall PA score is calculated by summing the results of all items \[20\]. PA levels were classified into 3 categories: inactive (\<600 MET-min/week), low PA level (600-3000 MET-min/week), and adequate PA level (\>3000 MET-min/week)

  at the enrollment

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The authors contacted the president of the national Behçet's Disease and Familial Mediterranean Fever Patients Association. The president invited members to participate in the study by e-mail.

You may qualify if:

• being age over 18
• being volunteer

You may not qualify if:

• ortopedic, neurologic, cardiopulmonary diseases that prevent physical activity
• psychological diagnosis and drug usage

Sponsors & Collaborators

• Halic University: lead

Study Sites (1)

Haliç University

Istanbul, Turkey (Türkiye)

Location

Related Publications (2)

• Oskay D, Tuna Z, Duzgun I, Elbasan B, Yakut Y, Tufan A. Relationship between kinesiophobia and pain, quality of life, functional status, disease activity, mobility, and depression in patients with ankylosing spondylitis. Turk J Med Sci. 2017 Nov 13;47(5):1340-1347. doi: 10.3906/sag-1702-93.

  PMID: 29151302 RESULT

• Giese A, Ornek A, Kilic L, Kurucay M, Sendur SN, Lainka E, Henning BF. Anxiety and depression in adult patients with familial Mediterranean fever: a study comparing patients living in Germany and Turkey. Int J Rheum Dis. 2017 Dec;20(12):2093-2100. doi: 10.1111/1756-185X.12297. Epub 2014 Jan 28.

  PMID: 24467729 RESULT

MeSH Terms

Conditions

Kinesiophobia; Motor Activity; Familial Mediterranean Fever

Condition Hierarchy (Ancestors)

Phobic Disorders; Anxiety Disorders; Mental Disorders; Behavior; Hereditary Autoinflammatory Diseases; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

• Seda Saka, PT, PhD

  Haliç University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PT PhD

Study Record Dates

• First Submitted: May 26, 2022
• First Posted: June 1, 2022
• Study Start: January 8, 2018
• Primary Completion: March 27, 2018
• Study Completion: December 20, 2018
• Last Updated: August 15, 2025

Record last verified: 2025-08

Locations

TU (1)