Clinical and Electrophysiological Evaluation of the Effectiveness for Manual Lymphatic Drainage

NCT05394870 | Completed

• 1 other identifier: 2022-03.02
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

When the other usage areas of the manual lymphatic drainage technique in the literature, except for the treatment of lymphedema, were examined recently, it was seen that it was also applied in orthopedic and neurological cases in a limited number of studies. The aim of our study is to investigate the effectiveness of manual lymphatic drainage on clinical and electrophysiological findings in carpal tunnel syndrome

Conditions

Carpal Tunnel Syndrome; Electrophysical Evaluation; Manual Lymphatic Drainage

Outcome Measures

Primary Outcomes (3)

• pressure pain threshold

  Each evaluation will be repeated 3 times with 10 seconds between measurements, and the data will be recorded by taking the average of the last two measurements (15). The patients will be evaluated by measuring the transverse carpal ligament, radioulnar joint and extensor digitorum muscle with an algometer before and at the end of the treatment. measurements will be recorded in kg/cm2

  15 minutes

• Boston Carpal Tunnel Questionnaire (BCTQ)

  BCTQ, a self-report measure of CTS, evaluates two domains: 1. The symptom severity scale (BCTQSS) has 11 items that assess pain, paresthesia, and weakness. 2. The functional status scale (BCTQ-FS) evaluates the ability to perform manual activities with 8 items. Each item evaluates the increasing severity of symptoms or difficulty with a high score.

  10 minutes

• Electrodiagnostic evaluation

  Median motor nerve latency, median motor nerve conduction velocity, compound muscle action potential amplitude will be measured at both levels. Median sensory nerve conduction studies will be performed by antidromic recording with a superficial electrode from the 3rd finger and a stimulus will be given from the wrist 14 cm proximal. Median sensory nerve latency, median sensory nerve conduction velocity and sensory nerve action potential will be calculated for both applications. nerve potentials will be calculated in m/sec

  15 minutes

Study Arms (2)

study group

EXPERIMENTAL

Other: manual lymphatic drainage (massage); Other: Splint treatment

control group

ACTIVE COMPARATOR

Other: Splint treatment

Interventions

manual lymphatic drainage (massage) OTHER

Patients will begin treatment with manual lymphatic drainage in the affected extremity. In this context, while the patients are in the supine hook position, lymph drainage will be applied first to the neck and then to the abdomen. After the stimulation of the central lymph nodes, the lymph circulation will be increased by stimulating the axillary lymph nodes of the relevant region. First, the proximal part will be drained and it will be advanced towards the distal. Drainage will be repeated depending on the edema at the distal forearm-wrist level.

study group

Splint treatment OTHER

The splint routinely given to patients diagnosed with mild to moderate carpal tunnel syndrome will be given to both groups in these patients

control group; study group

Eligibility Criteria

• Age: 20 Years - 55 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Diagnosis of mild to moderate carpal tunnel syndrome on electrodiagnostic examination
• Being between 20-55 years old
• Volunteering to participate in the treatment to be given

You may not qualify if:

• Have a systemic inflammatory disease
• Having any disease that may cause polyneuropathy, such as diabetes mellitus
• Cognitive impairment
• Receiving psychotherapy
• Having a pacemaker
• illiterate
• Having a disease affecting the central nervous system
• Having a hearing problem
• Any skin disease that would contraindicate manual lymphatic drainage
• Arterial or venous circulation disorder that would contraindicate manual lymphatic drainage

Sponsors & Collaborators

• Selcuk University: lead

Study Sites (1)

Kutahya Health Science University

Kütahya, Centrum, 43040, Turkey (Türkiye)

Location

Related Publications (1)

• Akdeniz Leblebicier M, Cihan E, Yaman F, Sahbaz Pirincci C, Ture A, Kavuncu V. Can manual lymphatic drainage be a new treatment option in mild-moderate carpal tunnel syndrome? A randomized controlled study. J Hand Ther. 2025 Jul-Sep;38(3):584-593. doi: 10.1016/j.jht.2024.12.020. Epub 2025 Feb 6.

  PMID: 39919926 DERIVED

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Interventions

Manual Lymphatic Drainage; Massage

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Therapy, Soft Tissue; Musculoskeletal Manipulations; Complementary Therapies; Therapeutics; Drainage; Physical Therapy Modalities; Rehabilitation

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: May 19, 2022
• First Posted: May 27, 2022
• Study Start: April 1, 2022
• Primary Completion: June 1, 2022
• Study Completion: June 10, 2022
• Last Updated: July 6, 2022

Record last verified: 2022-07

Locations

TU (1)