NCT05391685

Brief Summary

Purpose of the study: The aim of this study is to determine the effect of scar release techniques on chronic scar pain and mobility post cesarean section. Hypothesis:

  • H0: There is no effect of scar release techniques on chronic scar pain and mobility post cesarean section.
  • HA: There is effect of scar release techniques on chronic scar pain and mobility post cesarean section.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2022

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 21, 2022

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 26, 2022

Completed
25 days until next milestone

Study Start

First participant enrolled

June 20, 2022

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 20, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 20, 2022

Completed
Last Updated

May 26, 2022

Status Verified

May 1, 2022

Enrollment Period

3 months

First QC Date

May 21, 2022

Last Update Submit

May 21, 2022

Conditions

Outcome Measures

Primary Outcomes (4)

  • pain intensity

    The pain intensity will be assessed through visual analouge scale( VAS )for all participating women in both groups before and after the end of the treatment program. Each woman will be asked to mark a point on the line between the extremes that is related to her pain intensity.

    up to 4 weeks

  • Pressure pain threshold

    A pressure algometer will be used to measure pressure pain threshold (PPT)for all participating women in both groups before and after the end of the treatment program. PPT recording sites will be marked on the C-section scar at 2.5 cm intervals. This resulted in from 5 to 8 measurement points along the scar. Following, the marked points will be used to record PPTs in all time points for the PPT assessment; a 1-cm2 pressure probe will be positioned perpendicularly to the skin and pressed at a rate of 30kPa/s.Two measures will be collected for each area, with 30 second rest between point testing. Average pressure pain threshold (AvPPPT) (pressure points across worst 3 points on scar averaged) will be used for the analysis of the PPT data

    up to 4 weeks

  • Patient and Observer Scar Assessment Scale (POSAS)

    It will be used pre and post- treatment to assess the symptoms of pain and pruritus at the cesarean section scar for all participanting women of both groups before and after the end of the treatment program.

    up to 4 weeks

  • Scar adherence

    post cesarean section scar adherence will be assessted by an adheremeter for both groups before and after the end of treatment program. A mark will be made on the tightest part of the scar in four directions (superior, inferior, right and left). As there is no a contralateral side to abdominal tissue to be used as a reference range, we will use multi-directional scar mobility (MDM) . Scar mobility measurements across the points will be averaged for each participating women .

    up to 4 weeks

Secondary Outcomes (1)

  • Quality of life

    up to 4 weeks.

Study Arms (2)

therapeutic ultrasound

EXPERIMENTAL

Control group will be treated by therapeutic ultrasound only

Other: Scar release techniques + therapeutic ultrasound

therapeutic ultrasound+scar release techniques

EXPERIMENTAL

Study group will be treated by various scar release techniques in addition to therapeutic ultrasound

Other: Scar release techniques + therapeutic ultrasound

Interventions

Control group will be treated by therapeutic ultrasound only for2 sessions per week for two weeks Study group) will be treated by various scar release techniques in addition to therapeutic ultrasound, 2 sessions per week for two weeks.

therapeutic ultrasoundtherapeutic ultrasound+scar release techniques

Eligibility Criteria

Age25 Years - 35 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Women with a well healed, old , transverse cesarean section scar (more than 6 months resulted in chronic scar pain).
  • Pain can be intermittent or constant at rest or with activity, and it is reported to be at least at a level of about 3/ 10 on visual analogue scale at recording sites will be marked on the C-section scar at 2.5 cm intervals .
  • Women identified that the pain is either located in the cesarean section scar or caused by palpation of scar and it presents since the time of surgery not prior to the cesarean section.
  • Their ages will range from 25-35 years old.
  • Their BMI will be 18.5-29.9 kg/ m².
  • Voluntary acceptance to participate in the study.

You may not qualify if:

  • Women will be excluded if they have :
  • Acute and subacute cesarean section.
  • Delayed wound healing.
  • History of abdominal or pelvic cancer.
  • Active pelvic or abdominal infection.
  • Skin irritation/inflammation at the site of scar.
  • Currently pregnant women.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Ultrasonic Therapy

Intervention Hierarchy (Ancestors)

DiathermyHyperthermia, InducedTherapeutics

Central Study Contacts

manal Ahmed, lecturer

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Specialist of physical therapy at Elmansoura International hospital

Study Record Dates

First Submitted

May 21, 2022

First Posted

May 26, 2022

Study Start

June 20, 2022

Primary Completion

September 20, 2022

Study Completion

October 20, 2022

Last Updated

May 26, 2022

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will share
Shared Documents
STUDY PROTOCOL, SAP, ICF