Sensory Symptoms in Active Vitiligo
Sensory Symptoms as an Early Manifestation of Active Vitiligo: a Case-control Clinical and Molecular Study
1 other identifier
observational
90
0 countries
N/A
Brief Summary
This work aims to assess sensory symptoms in early active vitiligo patients (segmental, non-segmental, or mixed) and to measure 3 neuropeptides expression in their lesional skin \[neuropeptide Y(NPY), calcitonin gene-related peptide (CGRP), and nerve growth factors (NGF)\] to correlate neuropeptide levels, sensory symptoms, and functions, with criteria of disease activity and perceived stress scale.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started May 2022
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 20, 2022
CompletedFirst Posted
Study publicly available on registry
May 25, 2022
CompletedStudy Start
First participant enrolled
May 25, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 15, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
August 15, 2022
CompletedMay 25, 2022
May 1, 2022
3 months
May 20, 2022
May 20, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Neuropeptide
laboratory test
3 months
Study Arms (2)
Active vitiligo
Stable vitiligo
Interventions
Eligibility Criteria
Active vitiligo patients
You may qualify if:
- Active and stable vitiligo
You may not qualify if:
- Diabetic or other associated disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Related Publications (1)
El Sayed H, El Wakeel H, Nour Z, Mohyeeldeen R, Hafez V. Sensory Symptoms as an Early Manifestation of Active Vitiligo: A Case-Control Clinical and Molecular Study. Pigment Cell Melanoma Res. 2025 Jan;38(1):e13223. doi: 10.1111/pcmr.13223.
PMID: 39869070DERIVED
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr
Study Record Dates
First Submitted
May 20, 2022
First Posted
May 25, 2022
Study Start
May 25, 2022
Primary Completion
August 15, 2022
Study Completion
August 15, 2022
Last Updated
May 25, 2022
Record last verified: 2022-05