Treatment of Patients With Takayasu Arteritis Complicated With Pulmonary Artery Involvement
Observation of Long Term Effect of Medical and PTPA Treatment on Patients With Takayasu Arteritis Complicated With Pulmonary Artery Involvement
1 other identifier
observational
200
1 country
1
Brief Summary
- 1.Evaluate the effect of medical treatment and percutaneous transluminal pulmonary angioplasty on takayasu arteritis with pulmonary artery involvement
- 2.evaluate the efficacy of FAPI in predicting the activity and treatment efficacy of takayasu arteritis with pulmonary artery involvement
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2014
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 19, 2014
CompletedFirst Submitted
Initial submission to the registry
May 19, 2022
CompletedFirst Posted
Study publicly available on registry
May 24, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2042
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2042
December 20, 2023
January 1, 2023
29 years
May 19, 2022
December 14, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (8)
all cause death
all cause death
2014/1/1-2042/12/31
mean pulmonary arterial pressure change
change of mean pulmonary arterial pressure after treatment
2014/1/1-2042/12/31
pulmonary vascular resistance change
chagne of pulmonary vascular resistance after treatment
2014/1/1-2042/12/31
6MWD change
change of six minute walk distance after treatment
2014/1/1-2042/12/31
peak VO2 change
change of peak oxygen consumption after treatment
2014/1/1-2042/12/31
NT-proBNP change
change of NT-proBNP after treatment
2014/1/1-2042/12/31
RV/LV change
change of right ventricular end-diastolic diameter versus laboratory left ventricular end-diastolic diameterafter treatment
2014/1/1-2042/12/31
CI change
change of cardiac index after treatment
2014/1/1-2042/12/31
Interventions
Percutaneous transluminal pulmonary angioplasty
Eligibility Criteria
patients diagnosed with Takayasu arteries with pulmonary arteries involvement received either medical or percutaneous transluminal pulmonary angioplasty
You may qualify if:
- patients diagnosed with Takayasu arteries with pulmonary arteries involvement
You may not qualify if:
- Patients had pulmonary artery stenosis arising from CTEPH, fibrosing mediastinitis and congenital pulmonary artery stenosis
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College
Beijing, 100000, China
Study Officials
- PRINCIPAL INVESTIGATOR
zhihong Liu, doctor
Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 19, 2022
First Posted
May 24, 2022
Study Start
January 19, 2014
Primary Completion (Estimated)
December 31, 2042
Study Completion (Estimated)
December 31, 2042
Last Updated
December 20, 2023
Record last verified: 2023-01
Data Sharing
- IPD Sharing
- Will not share