NCT05387980

Brief Summary

The purpose of this study is to learn about the safety and effectiveness (how well the study treatment works) of the study medicine (CIBINQO) for the potential treatment of atopic dermatitis in people under Japanese medical practice.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,128

participants targeted

Target at P75+ for all trials

Timeline
31mo left

Started Apr 2022

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress62%
Apr 2022Nov 2028

Study Start

First participant enrolled

April 19, 2022

Completed
20 days until next milestone

First Submitted

Initial submission to the registry

May 9, 2022

Completed
15 days until next milestone

First Posted

Study publicly available on registry

May 24, 2022

Completed
6.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2028

Last Updated

March 19, 2026

Status Verified

March 1, 2026

Enrollment Period

6.5 years

First QC Date

May 9, 2022

Last Update Submit

March 17, 2026

Conditions

Keywords

JAK InhibitorAtopic Dermatitis (AD)AbrocitinibEczema

Outcome Measures

Primary Outcomes (2)

  • Number of Participants with adverse drug reactions

    156 weeks

  • Number of Participants with Discontinuation of Treatment

    156 weeks

Secondary Outcomes (4)

  • Percentage of Participants Achieving Investigator's Global Assessment (IGA) Score

    Baseline, 156 weeks

  • Percentage of Participants with Change From Baseline in Eczema Area and Severity Index (EASI)

    Baseline, 156 weeks

  • Percentage of Participants with Change From Baseline in Affected % Body Surface Area (BSA)

    Baseline, 156 weeks

  • Percentage of Participants with Change From Baseline in Pruritus Assessment

    Baseline, 156 weeks

Study Arms (1)

Patients receiving CIBINQO

Patients receiving CIBINQO tablets by mouth for the treatment of Atopic Dermatitis.

Drug: CIBINQO

Interventions

Patients receiving CIBINQO tablets by mouth for the treatment of Atopic Dermatitis.

Patients receiving CIBINQO

Eligibility Criteria

Age12 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Adolescent participants diagnosed with atopic dermatitis in Japan.

You may qualify if:

  • Participants receiving this Product for treatment of AD.
  • Participants start receiving this Product (commercial product) for the first time and no earlier than the contract date of this Study, or Participants who continues to receive this drug after hospital transfer can be registered retrospectively.

You may not qualify if:

  • \. Participants previously enrolled in this Study at the same site.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pfizer Local Country Office

Tokyo, Japan

Location

Related Links

MeSH Terms

Conditions

Dermatitis, AtopicEczema

Condition Hierarchy (Ancestors)

Skin Diseases, GeneticGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesDermatitisSkin DiseasesSkin and Connective Tissue DiseasesSkin Diseases, EczematousHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • Pfizer CT.gov Call Center

    Pfizer

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 9, 2022

First Posted

May 24, 2022

Study Start

April 19, 2022

Primary Completion (Estimated)

November 1, 2028

Study Completion (Estimated)

November 1, 2028

Last Updated

March 19, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Pfizer will provide access to individual de-identified participant data and related study documents (e.g. protocol, Statistical Analysis Plan (SAP), Clinical Study Report (CSR)) upon request from qualified researchers, and subject to certain criteria, conditions, and exceptions. Further details on Pfizer's data sharing criteria and process for requesting access can be found at: https://www.pfizer.com/science/clinical\_trials/trial\_data\_and\_results/data\_requests.

Locations