NCT05385094

Brief Summary

This study aim to compare different measures of renal function (glomerular filtration rate) in ICU patients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
5,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2006

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2006

Completed
12 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2017

Completed
4 years until next milestone

First Submitted

Initial submission to the registry

December 12, 2021

Completed
5 months until next milestone

First Posted

Study publicly available on registry

May 23, 2022

Completed
2.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2024

Completed
Last Updated

May 23, 2022

Status Verified

May 1, 2022

Enrollment Period

12 years

First QC Date

December 12, 2021

Last Update Submit

May 19, 2022

Conditions

Critical Illness

Outcome Measures

Primary Outcomes (2)

  • Correlations between estimates of renal function

    7 days

  • Correlations between changes in estimates of renal function

    7 days

Interventions

S Creatinine concentrationDIAGNOSTIC_TEST
Serum Cystatin C concentrationDIAGNOSTIC_TEST
Urinary Creatinine ClearanceDIAGNOSTIC_TEST

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

General ICU patients

You may qualify if:

  • ICU patients with at least one measurement of urinary creatinine clearance

You may not qualify if:

  • Renal replacement therapy initiated before the measurement of creatinine clerance

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Karolinska University Hospital Solna

Stockholm, 17176, Sweden

Location

MeSH Terms

Conditions

Critical Illness

Condition Hierarchy (Ancestors)

Disease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Profesor, Senior Consultant

Study Record Dates

First Submitted

December 12, 2021

First Posted

May 23, 2022

Study Start

January 1, 2006

Primary Completion

December 31, 2017

Study Completion

December 31, 2024

Last Updated

May 23, 2022

Record last verified: 2022-05

Locations

SE(1)