Prior Abdominal Surgery: A Potential Risk Factor for Colonic Diverticulosis or Diverticulitis

NCT05384925 | Completed

• 1 other identifier: 0107-20
• Study Type: observational
• Target: 359
• Locations: 1 country
• Sites: 1

Brief Summary

Background \& Aims: Abnormal colonic pressure profiles have been associated with an increased risk of colonic diverticulosis. A surgical history is a known risk factor for abdominal adhesions, and these may lead to increased intraluminal colonic pressure. We assessed whether previous abdominal surgery is associated with colonic diverticulosis or diverticulitis. Methods: The investigators analyzed data from a prospective study of patients undergoing colonoscopy for different indications from 2020 through 2021. Patients completed a structured questionnaire concerning previous abdominal surgeries, dietary and lifestyle exposures including smoking and alcohol use, and co-morbidities.

Conditions

Diverticulosis, Colonic; Abdominal Adhesion; Diverticulitis

Outcome Measures

Primary Outcomes (1)

• correlation between prior abdominal surgery and the development of diverticulosis

  the investigators are willing to see if prior abdominal surgery raise the patient's risk of developing future diverticulosis. The investigators use questionere to collect data from patients. The final measurements will be calculatrd with spss software

  in the end of the study (estimated in 1 year)

Interventions

comparison OTHER

abdominal surgery as a risk factor for diverticulosis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients 18 years of age and older presenting for a colonoscopy at Shamir Medical Center between 2020 and 2021

You may qualify if:

• patients \> 18 years old who are going through colonoscopy in shamir medical center for any reason

You may not qualify if:

• inadequate preparation (Boston Bowel Preparation Quality Scale \<6);
• previous colonic resection based on history and colonoscopy;
• previous colon cancer.

Sponsors & Collaborators

• Assaf-Harofeh Medical Center: lead

Study Sites (1)

Asag Harofeh Medical Center

Be’er Ya‘aqov, 70300, Israel

Location

MeSH Terms

Conditions

Diverticulosis, Colonic; Diverticulitis

Condition Hierarchy (Ancestors)

Colonic Diseases; Intestinal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Diverticular Diseases; Gastroenteritis

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: May 12, 2022
• First Posted: May 20, 2022
• Study Start: April 12, 2020
• Primary Completion: May 22, 2021
• Study Completion: April 1, 2022
• Last Updated: May 26, 2022

Record last verified: 2022-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE

Locations

IL (1)