NCT05374018

Brief Summary

This is an epidemiology study for the prevalence and serotypes of pneumococcus pneumoniae in hospitalized patients with community acquired pneumonia (CAP). The serotypes of the pneumococcus pneumoniae will be determined by a urinary antigen assay

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,800

participants targeted

Target at P75+ for all trials

Timeline
13mo left

Started Dec 2021

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress81%
Dec 2021Jun 2027

Study Start

First participant enrolled

December 1, 2021

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

May 10, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 13, 2022

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2026

Completed
1.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2027

Expected
Last Updated

March 18, 2026

Status Verified

March 1, 2026

Enrollment Period

4.2 years

First QC Date

May 10, 2022

Last Update Submit

March 17, 2026

Conditions

Pneumonia

Outcome Measures

Primary Outcomes (1)

  • prevalence of strep pneumonia

    to determine prevalence

    2 years

Interventions

urinary kit for pneumococcus antigen assayDIAGNOSTIC_TEST

urine test for detection of pneumococcus antigen

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients admitted for CAP

You may qualify if:

  • Admitted with signs and symptoms suggestive of pneumonia which include one or more of the followings:
  • fever
  • CXR changes with consolidation, increased alveolar shadowing or hazziness
  • respiratory symptoms like increase shortness of breath, cough with sputum Raised inflammatory markers suggesting of bacterial infection with either increased white cell count or C-reactive protein, or both

You may not qualify if:

  • Nosocomial pneumonia which is acquired \>= 48 hours after hospital admission. Pneumonia which are already known to be caused by pathogens other than pneumococcus pneumoniae.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Medicine and Therapeutics, Prince of Wales Hospital, CUHK

Shatin, Hong Kong

Location

MeSH Terms

Conditions

Pneumonia

Condition Hierarchy (Ancestors)

Respiratory Tract InfectionsInfectionsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof.

Study Record Dates

First Submitted

May 10, 2022

First Posted

May 13, 2022

Study Start

December 1, 2021

Primary Completion

January 31, 2026

Study Completion (Estimated)

June 30, 2027

Last Updated

March 18, 2026

Record last verified: 2026-03

Locations

HK(1)